| Objective: We comparatively analysis the clinical curative effect with the mitral valve repairment(MVP)and mitral valve replacement(MVR)in the treatment of mitral valve regurgitation disease respectively,and summariz the advantages and disadvantages,indications and clinical prognosis of these two kinds of surgical methods.Methods: We retrospectively analysis the clinical date of 103 patients with mitral regurgitation disease treated by surgecal mathods in the cardiac department of Yijishan hospital affiliated to Wannan medical college between July 2012 to July 2017.We divided these103 case into two groups according to the surgical methods.Of these 103 patients,there were 41 cases treated by MVP and other 62 patients by MVR.We collected these patients’ clinical date about preoperative cardiac function grading,left ventricular diastolic(LVEDD),left atrial diameter(LAD),left ventricular(LVESD)and left ventricular ejection fraction(EF).Intraoperative extracorporeal circulation time,crossclamping time,blood transfusion volume and flow rate,length of hospital stay,postoperative left atrial diameter,LVESD,LVEDD,left ventricular ejection fraction and complications during the follow-up period,and then analysised these factors repectively.Results:During the follow-up of the average(13.2 ± 6.41)months,the postoperative cardiac function was significantly improved in both groups.The EF、LAD、LVESD、LVEDD was significantly improved in both groups.(P< 0.05).The patients in the MVP group were slightly longer than those with MVR in CPB time(P< 0.05).There was no significant difference in the amount of blood transfusion in the MVP group,24 hours after surgery,and the total length of hospitalization compared with the MVR group(P〉0.05).The gender and age of the two groups were not statistically significant.During the follow-up of the MVR group,there were two cases of cerebral hemorrhage associated with anticoagulation.Conclusion:: 1.Both MVR and MVP are effective surgical methods in the treatment of mitral regurgitation disease,and they all can correct valve reverse flow and improve the patient’s cardiac function.2.The in CPB time and the crossclamping time in the patients of the mitral valve replacement group was shorter than that in the mitral valve repairment group.3.The patients’ left ventricular function in the MVP group were better than that in the MVR group.4.The cardiovascular complications in MVR group was slightly higher than that in the MVP group,but the overall complications of the two groups were not statistically significant. |