Study On Characteristics Of Distribution Of Constitution Types Of Chinese Medicine In Elder Patients With HIV/AIDS In Guangxi

Objective: To observe the status quo of constitution types of Chinese medicine in elder patients with HIV/AIDS,by studying the characteristics distribution of constitution types of Chinese medicine in elder patients with HIV/AIDS in Guangxi.The purpose is to provide new idea for clinical treatment,and provide the reference of TCM for elderly AIDS,and then improve the efficacy of clinical application in TCM,then there is that improve the quality of elderly HIV/AIDS patients’ life.Methods: A multi-stage cluster sampling method was used to collect the research objects.The research object is the elderly HIV/AIDS patients who are from LuZhai County Chinese Hospital and LuZhai County People’s Hospital from October 2015 to June 2017.To facilitate follow-up and prevent cases from shedding too much,and the selected subjects were mainly local residents.Among them,the subjects must meet the diagnostic criteria in the Third Edition of the AIDS Diagnosis and Treatment Guidelines(2015)whose age≥50 years old,and must be aware of the entire investigation process and be willing to cooperate and sign informed consent.According to the method of field epidemiology,"TCM constitution classification and determination table" was filled out in the form of questionnaire.Then according to the judgment method,the scores in the questionnaire are given and calculated,and the type of TCM constitution is determined based on the final converted results.lso collect respondents’ general information,related to time nodes and values,such as name,gender,age,nationality,contact information,confirmed time,start antiviral time,time to start taking Chinese traditional medicine as well as the original and recent CD4+T readings,etc.According to the Classification and Determination of Traditional Chinese Medicine,there are nine types of constitution.According to the requirement of multivariate statistical analysis for sample size,it was determined that at least 180 samples should be included in the project.In view of the loss of part of the study subjects,a total of 216 samples should be included in the inclusion of 120%.After excluding the shedding objects,a total of 215 samples were included in this study finally.The data was entered by Microsoft Office Excel.Different statistical methods are selected according to the characteristics of data,SPSS22.0 statistical software was used to perform centralized and discrete trend descriptions on basic information and laboratory testing indicators.The measurement data of general information and blood test values were described by means of the mean plus or minus standard deviation.The missing blood test value is complemented by the average of the corresponding groups.Statistical tests were performed on all variables in the target population,and t-test was applied to the normal distribution.Non-parametric test was used if the normal distribution was not consistent.P<0.05 was considered to be statistically significant.Results:(1)The number of moderate type constitution of elderly HIV/AIDS patients was 118(54.9%)and the number of qi deficiency constitution was32(14.9%),moderate type which partial qi-deficiency was 26(12.1%),yang deficiency constitution was 14(6.5%),moderate type which partial yang-deficiency was 2(0.9%),yin deficiency constitution was 3(1.4%),moderate type which partial yin-deficiency was 2(0.9%),dampness-heat constitution was 4(1.9%),moderate type which partial dampness-heat was2(0.9%),qi stagnation constitution was 2(0.9%),moderate type which partial qi-stagnation was 2(0.9%),blood stasis constitution was 3(1.4%),phlegmatic hygrosis constitution was 1(0.5%),moderate type which partial phlegmatic-hygrosis was 1(0.5%),both qi and yang deficiency was 2(0.9%),both yin and qi deficiency was 1(0.5%).(2)After treatment,the count of CD4+T cell of moderate type,moderate type which partial qi-deficiency and qi deficiency constitution were increased with significant difference(P < 0.01),and there was no difference among CD4+T cell count of yang deficiency constitution(P >0.05).There was no difference among CD4+T cell count of all types of Chinese medicine constitution after treatment(P>0.05).(3)Before and after treatment,there were differences of CD4 +T cell counts in integrated Chinese and western medicine group(143cases),HAART group(64 cases),and all the patients(215 cases)(P<0.01),but there was no difference in Chinese medicine group(8 cases)(P>0.05).Conclusion: The constitutions types of Chinese medicine in elderly with HIV/AIDS are mostly moderate type,qi-deficiency type and type of moderate partial qi-deficiency.These types of constitution are related to the improvement of the condition.The TCM constitution type has limited effects on the efficacy of HAART.