Therapeutic Effect Of Tanshinone ⅡA-sulfonic Sodium On HLAP Patients And Its Influence On Blood Lipid Levelsand SCRP

Objective:To explore therapeutic effect of Sodium tanshinone ⅡA sulfonate(STS)on Hyperlipidemic Acute Pancreatitis(HLAP)patients and its influence on blood lipid levels and sCRP;Methods:By collecting clinical case-control study method to analysis the curative effect of STS in the HLAP.Fifty-two patients with HLAP who meet the criteria were in the present study from the Affiliated Hospital of Guilin Medical Universty,Twenty-three of these 46 patients were treated STS,theothers were no use,Control group given conventional treatment of acute pancreatitis(starvation treatment、gastrointestinal decompression、monitoring、fluid resuscitation 、 no fat nutrition support 、 inhibit the secretion of pancreatic enzymes and pancreatic enzyme activity、anti-infection、preven prevent and treat intestinal failure、symptomaticTreatment),We measured the changes of blood biochemical indexes after intervention(7days),including triglyceride、sCRP.The date were Spss22.0 statistic software foranalysis.Measurement date,expressed as mean ± standard,The two groups before and after treatment compared with independent sample t-test,the same group were compared with the single factor analysis of variance.Inspection level a=0.05,P>0.05 difference not statistically significant(P<0.05)difference was statistically significant.Results:STS treatment significantly decreased the levels of sCRP,TG in patients with HLAP,as compared with the control group,and the decline was greater in STS group.The difference has statistically significant.Conclusion:STS can declines inflammation index in patients with HLAP,and have certain curative effect of blood lipid.