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Analysis Of Clinical Features Of Tachycardia-Induced Cardiomyopathy

Posted on:2019-12-02Degree:MasterType:Thesis
Country:ChinaCandidate:Y Q ChenFull Text:PDF
GTID:2394330545476216Subject:Internal medicine
Abstract/Summary:PDF Full Text Request
Objective:1.To observe and compare the clinical features of patients of Tachycardia-Induced Cardiomyopathy and dilated cardiomyopathy;2.Comparison of echocardiography changes before and after treatment of tachycardia-Induced cardiomyopathy;3.Comparison of echocardiography Differences in Rhythm Control and Ventricular Control of Tachycardia-induced Cardiomyopathy.Methods:Retrospectively collected from June 2010 to June 2017 in Hunan Provincial People’s Hospital discharged from the Department of Cardiology was diagnosed as "tachycardia-induced cardiomyopathy"patients with regular follow-up,record patient baseline data.After 6 months of treatment,these patients were reexamined in our outpatient department and the results of echocardiography were recorded during the review.At the same time,patients from the Department of Cardiology at the People’s Hospital of Hunan Province from June 2010 to June 2017 were collected and patients diagnosed with dilated cardiomyopathy were identified as controls.Comparing the clinical data of patients with tachycardia-induced cardiomyopathy and dilated cardiomyopathy,compare the change of echocardiography before and after treatment in patients with tachycardia-induced cardiomyopathy,and further divide into rhythm control group and rate control group according to different treatment methods,compared the echocardiographic changes of the two treatment methods.Results:1.A total of 32 patients with tachycardia-induced cardiomyopathy were included in this study.Among them,20 were male patients with an average age of51.19±18.61 years.Among the causes of tachycardia-induced cardiomyopathy,13patients were atrial fibrillation and 6 patients were ventricular tachycardia.8 patients was atrial tachycardia,atrioventricular reentrant tachycardia was 2,2 patients had atrial flutter,1 patient had atrial fibrillation with atrial flutter,baseline left ventricular ejection fraction was(35.1±9.2)%,The tachyarrhythmia burden was(65.2±36.5)%.Radiofrequency ablation was performed in 12(37.5%)patients and drug treatment was performed in 20(62.5%)patients.2.Compared with patients with dilated cardiomyopathy,palpitations were more common in patients with tachycardia-induced cardiomyopathy(3.1%vs.84.4%;P<0.001),and higher tachyarrhythmia burden of(64.4± 37.2 vs.1.3 ± 0.6;P<0.001),NT-proBNP levels were lower(P<0.002),whereas left bundle branch block and abnormal Q waves were more common in patients with dilated cardiomyopathy(all P<0.05),and in dilated cardiomyopathy Among the patients,left atrial diameter(40.8 ±5.6 vs.47.4 ± 8.9;P<0.001)and left ventricular end diastolic diameter(53.0 ± 7.5 vs.72.0 ± 10.5;P<0.001)expanded more significantly,and left ventricular ejection fraction was lower(35.1 ± 9.2 vs.24.6±7.9;P<0.001).3.After radiofrequency ablation and drug therapy in 32 patients,the left atrial diameter(40.8 ± 5.6 vs.37.2 ± 6.1;P<0.001)and left ventricular end-diastolic diameter(53.0 ± 7.5 vs.49.5 ± 6.3;P<0.001)were significantly reduced.Left ventricular ejection fraction was significantly improved(35.1 ± 9.2 vs.52.2 ± 12.1;P<0.001).Compared with the ventricular rate control group,the diameter of the left atrium in the rhythm control group was significantly reduced(35.1 ±5.1 vs.39.8 ± 6.5;P<0.01),the left ventricular ejection fraction improved more significantly(52.2 ± 12.1 vs.46.0 ± 9.3;P<0.01).Conclusions:1.Compared with patients with dilated cardiomyopathy,the degree of heart function deterioration and left ventricular dilatation in patients with tachycardia-induced cardiomyopathy are mid;2.rhythm control treatment is superior to ventricular rate control in the degree of left atrial diameter and left ventricular ejection fraction recovery treatment.
Keywords/Search Tags:Heart failure, Tachycardia-Induced Cardiomyopathy, Dilated Cardiomyopathy, Amino-terminal pro-brain natriuretic peptide, Ablation
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