The Effect Of Drug-coated Balloon In The Treatment Of In-stent Restenosis In Lower Limb Atherosclerosis Obliterans

Objective :To observe near-medium term clinical outcome of drug-coated balloon in treatment of in-stent restenosis(ISR)after stent implantation in superficial femoral artery of lower limb atherosclerosis obliterans.Method:From Sep 2015 to Oct 2017,36 patients(36 limbs)were diagnosed with in-stent restenosis of superficial femoral artery after stents be placed at China-Japan union hospital of Jilin University in department of Vascular Surgery,and their clinical data were analyzed retrospectively.Main lesion types: 29 limbs of target vascular stenosis and 7 limbs with complete occlusion.According to the clinical treatment,they were divided into two groups: ordinary balloon angioplasty in 18 cases(group A).Drug-coated balloon angioplasty in18 cases(group B).Postoperative follow-up of 3~12 months,the postoperative clinical effect between the two groups were compared,through the relief of clinical symptoms,ankle brachial index(ABI),target vascular patency rate,mortality and amputation rate.Results:In 36 patients,the operation success rate was 100%,the operation time was 60-100 min,and the correlative complications(Such as: Vascular rupture,local thrombosis,stent rupture,distal embolization)were not present in the operation.Postoperative DSA : target vascular of morphology and ventilation were good.After operation,the patients were given the routine medication in hospital for 1 week and took orally dual antiplatelet drug outside hospital.36 patients were followed up.The follow-up time was 3~12 months.The primary patency rates of 6 months was(group A)72.2%(13/18)and(group B)100%(18/18).The12-month primary patency rates was(group A)50%(9/18)and(group B)88.9%(16/18).No amputation or death during Postoperative follow-up.Conclusion:Drug-coated balloon angioplasty has an obvious advantage in the treatment of superficial femoral artery in-stent restenosis compared with ordinary balloon angioplasty.