Changes Of Blood Lipids And Heart Function In Coronary Heart Disease Patients With Subclinical Hypothyroidism

Objective:To investigate changes of blood lipids and heart function in coronary heart disease patients with subclinical hypothyroidism.Methods:A total of 173 patients with coronary heart disease diagnosed by coronary angiography during the period from October 1,2014 to October1,2017 in the Department of Cardiology,China-Japan Union Hospital of Jilin University were enrolled in this study.According to the thyroid function,the patients divided into the subclinical hypothyroidism group(68 cases)as the case group and the normal thyroid function group(105cases)as the control group.Analyze and compare whether the two groups have differences in the risk factors affecting coronary heart disease,and whether there are differences in heart function.Results:The levels of total cholesterol and triglyceride in the subclinical hypothyroidism group were higher than those in the normal thyroid function group(P<0.05).The E / A value of Echocardiography in the subclinical hypothyroidism group was lower than that in the normal thyroid function group(P < 0.05).There was no significant differencebetween the two groups in other biochemical parameters,hypertension,blood sugar and ejection fraction(P>0.05).Conclusion:Patients with subclinical hypothyroidism and coronary heart disease are more likely to have elevated serum total cholesterol and triglycerides than those with simple coronary heart disease,and more likely to have decreased diastolic function.Early detection and intervention should be taken to avoid exacerbation of coronary artery disease in patients with coronary heart disease,and even worsened from subclinical hypothyroidism to hypothyroidism and hypothyroid heart disease.