| Objectives To observe the clinical effect of the interventional therapy in patients with stable angina pectoris by observing the blood flow reserve score(FFR),and to explore its guiding value in the interventional therapy of patients with stable angina.Methods Continuous selection method in July 2015 to February 2017 in tangshan worker hospital heart medicine diagnosis for stable angina,parallel coronary angiography(the CAG)check,reference vessel diameter>2.5 mm,hints of coronary arterial stenosis degree between 40% ~ 90% of the 79 cases of patients into the study,aged 45 to 80 years old,average age(65.56±9.53 mm),47 patients with male,female patients 32 cases,were randomly divided into FFR(39cases)and the CAG group(40cases),respectively improve the FFR and coronary angiography examination examination,FFR group,FFR 0.8 or less as placing stents indications,the CAG group,on the basis of the measured narrow degree decide whether PCI treatment lesions.Two groups of patients were given standard anti-coronary medication before and after surgery.Postoperative 1 month,6 months,12 months follow-up,compared two groups of number of stents,was in the hospital again and the heart major adverse cardiovascular events(MACE)including(recurrence angina pectoris,myocardial infarction,cardiac death,ischemia lead to target vessels again reascularization),comparison of the differences between two groups of patients prognosis.Results A total of 81 patients were enrolled in this study,and 79 cases were included in the final statistical analysis.Age 45-80,average age(65.56±9.53);There were 47 males and 32 females.The 39 patients in the FFR group were involved in coronary artery disease in 77,and 40 patients in the CAG group had 79 cases of coronary artery disease.1 There was no statistical difference in the basic clinical conditions of the two groups,such as gender,age,and risk factors of cardiovascular disease.2 Two groups of coronary angiography in patients with pathological feature such as distribution characteristics(single,double,multiple branch),number of lesions,the degree of coronary artery stenosis,Gensini score distribution of no statistical difference.3 All the lesions in the FFR group were implanted with 29 stents,45 were implanted in the CAG group,and the number of stent implantation in FFR group was significantly lower than that in the CAG group,and the difference was statistically significant(P < 0.05).4 Follow-up: two groups of patients were followed up for 1 month and 6 months after surgery: there was no statistical difference between the two groups in the proportion of rehospitalization and the incidence of MACE events(P > 0.05).Follow-up of 12 months after operation: 3 patients in FFR group had recurrent angina,and the incidence rate was 7.7%.There were 2 patients in the hospital with a rate of 5.1%.One of the patients suffered from frequent angina pectoris and percutaneous coronary intervention.There were 12 patients with recurrent angina pectoris in CAG group,and the incidence rate was 30%.There were 10 patients in the hospital with a 25% incidence.Among them,one patient was treated with revascularization in the stent restenosis,and the other two patients were treated with poor prognosis.Two groups of patients were followed up for 12 months after surgery: the difference between the two groups was statistically significant(P < 0.05).Conclusions 1 For patients with stable angina,1 month,6 months follow-up the CAG and joint FFR to guide the CAG incidence of MACE and hospitalization in patients with no statistical difference,the prognosis of patients with no obvious difference in both groups.2 There was a statistical difference in the number of implanted scaffolds,and FFR guided intervention could reduce the number of stent use.3 There was a statistically significant difference between the recurrence of angina and rehospitalization after 12 months of follow-up in both groups,and the combined FFR guidance could significantly reduce the recurrence rate and rehospitalization rate of the patients. |
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