The Clinical Value Of MR Diffusion Tensor Imaging And Susceptibility Weighted Imaging In The Early Diagnosis Of Mild Traumatic Brain Injury

Objective: To explore the clinical value of MR diffusion tensor imaging,diffusion tensor tractography technique and susceptibility weight imaging in the early diagnosis of mild traumatic brain injury.Methods: Routine MR sequences and diffusion tensor imaging(DTI),susceptibility weighted imaging(SWI)was performed on 15 mild traumatic brain injury patients and 15 age-and sex-matched control subjects.Fractional anisotropy value(FA)and apparent diffusion coefficient value(ADC)were measured in bilateral centrum semiovale,thalamus,posterior limb of internal capsule,cortex of frontal lobe,genu of corpus callosum,splenium corporis callosi of MTBI and controls.The results were compered between two groups.DTI-tractography was performed on all patients.Result: Microbleeds was detected in one patient of brainstem in SWI.FA value of MTBI were significantly decreased in left-forntallobe in 0.447±0.028,right-splenium corporis callosi in 0.560±0.031,compared with controls(left-forntallobe in 0.469±0.021,right-splenium corporis callosi in 0.584±0.025),and the P<0.05(P=0.021,P=0.029).FA value in other regions were decreased,but the differences was not significantly.The ADC value were increased in centrum semiovale,frontal cortex and corpus callosum,while posterior lime of internal capsule,thalamus,corpus callosum were decreased,and the change were not significantly.Conclusion: DTT can show the damage of fiber bundles noninvasively.Combined with SWI and DTI can detected the microstructure changes of brain tissue in early stage of MTBI by quantitative analysis,which is helpful to improve the early diagnosis rate of MTBI and provided a basis for clinical estimate.