Clinical Analysis Of The Impact On The Prognosis And Reproduction Outcome Derived From Based On Fertility-sparing Surgery In Borderline Ovarian Tumor

Objective: Survey the pregnancy outcome,prognosis,recurrence,and so on of the Borderline ovarian tumors' patients who underwent fertility-sparing surgery to find out whether it is necessary to do comprehensive staging surgery,lymph node excision or not,and the effect of different operative methods for postoperative pregnancy and recurrence.Methods: Collect the clinical data of the borderline ovarian tumors' patients who suffered the conservative surgery and are less than 40 years old at the Shengjing Hospital affiliated to China Medical University between January 1,2006 to December 31,2016.Retrospectively analyzed the clinical data and follow-up by telephone and outpatient.Analyze the interrelationship of pregnancy outcome,prognosis,recurrence,to the clinical data by the statistical method.Results: 142 patients who accepted the surgical treatment of preserving fertility function,mean age is 28.56±5.24 years old.Complete staging surgery 39 cases(27.46%),incomplete staging surgery 103 cases(72.54%),for both pregnancy and recurrence,no significant difference between the both.Similarly between 21 cases of re-staging surgery and 121 cases of no secondary surgery,both in terms of recurrence,pregnancy had no statistical significant difference.Specific operation methods for reproductive function retaining contain unilateral ovarian cystectomy 26 cases(18.31%),unilateral salpingo-oophorectomy 73 patients(51.41%),bilateral ovarian cystectomy 20 cases(14.08%),unilateral salpingo-oophorectomy with the contralateral ovarian cystectomy 23 cases(16.20%).There is no statistical difference in operation methods for recurrence,but significant differences exist about postoperative pregnancy(P < 0.05).Conclusions: Episode age of Borderline oarian tumor is little,fertility-preserving operation is needed and feasible,but should pay attention to follow-up closely.Restaging surgery is not necessary when comprehensive staging surgery was not achieved at the first time to do the operation,but close follow-up is necessary.when the lesions can be cut completely,the tumor is not huge and fragile,laparoscopic can improve postoperative pregnancy rate,meanwhile there is no statistical difference in recurrence rate to the laparotomy.Among different operation methods,the more the ovarian tissue remain,the higher postoperative pregnancy rate is.At the same time,the the recurrence rate is not significant different.