The Correlation Exploration Between Pa-etCO2 And Clinical Outcomes Of Patients With AECOPD

Background:PetC02 is a test for exhaled breath components,which can reflect the degree of dioxide retention in patients with COPD.The current study related with PetC02,all uses it as a non-invasive alternative scheme to PaC02.Our study indicates that the difference between PaC02 and PetC02 can reflect the patient's dead space ventilation.The exploration of correlation between the clinical outcomes of Pa-etC02 and AECOPD patients has not been reported in the literature,and its specific reference range is not yet clear.Objective:To analyze the significance of Pa-etC02 as a predictor of clinical outcome in patients with AECOPD by comparing PetC02,PaC02,and Pa-etC02 in patients with AECOPD.Methods:To retrospectively analyze PetC02,PaC02,Pa-etC02 of 131 patients with AECOPD that is divided into groups according to the clinical outcomes,and to conduct the statistical comparison.Results:The mean value of Pa-etC02 in 69 patients with negative clinical outcome was-6.87±0.75 mmHg,95%confidence interval[-8.36-5.37];the mean value of Pa-etC02 in 62 patients with positive clinical outcome was 6.48±1.10 mmHg,95%confidence interval[4.27 8.70],F<0.05,P=0.00.Conclusion:Under the condition of PaC02>39.46 mmHg,4.27<Pa-etC02<8.70 is a sign of poor clinical outcome in patients with AECOPD.