| Objective: Retrospectively analyze the clinical efficacy(VAS score,JOA score,operative segment,adjacent segment activity,cervical motion)of ACDF operation(anterior cervical discectomy+ cage interbody fusion + titanium plate internal fixation)and ProDisc-C artificial cervical disc replacement on single segment cervical spondylosis as well as their safety differences(operation time,intraoperative blood loss,postoperative complications),exploring their significances.Method: Collect the data of patients with single segmental nerve root cervical spondylosis or cervical spondylotic myelopathy admitted to subsidiary hospital from March,2012 to March 2014,respectively analyzing 30 cases meeting the criteria of diagnosis,inclusion and exclusion,among which 15 patients were carried out ACDF operation,15 were treated with ProDisc-C artificial cervical disc replacement.The preoperative,intraoperative and postoperative data of two groups were recorded,including efficacy index(VAS score,JOA score,surgical segment and adjacent segment activity,cervical motion)and safety index(operation time,intraoperative blood loss,postoperative complications)and the statistical analysis of the result was did.Results: 1.The differences of the two groups were not statistically significant in gender,age,disease duration,surgical segment,preoperative VAS score,preoperative JOA score,preoperative surgical segment and adjacent segment activity,preoperative cervical motion and other aspects(P >0.05).2.There was no statistical significance between the two groups in operation time and operative blood loss,(P >0.05).3.At the end of the follow-up,the JOA score and VAS score of the two groups were significantly improved compared with preoperative period,the difference was statistically significant,but the comparative difference between the two groups was not statistically significant(P>0.05).4.At the end of the follow-up,compared with preoperative period,the P value of the operative segment and adjacent segment activity of Group ProDisc-C was higher than 0.05,and there was no statistical significance;the P value of the operative segment and adjacent segment activity,and cervical motion of Group ACDF was less than 0.5,which was statistically significant in comparison with preoperative period.Conclusion: 1.The clinical efficacy of Group ProDisc-C was similar to the Group ACDF in relieving the compression and recovery of nerve function,both of them achieved relatively satisfactory results.2.There was no significant difference in Group ProDisc-C in postoperative segmental activity,adjacent segment activity and cervical motion compared with preoperative physiological activity of cervical spine.It was improved compared with Group ACDF,which can preserve the surgical segment and the overall activity of the cervical spine but not increase adjacent segment activity. |