| PurposeTo investigate the correlation between the tumor weight,pathological volume and CT or MR imaging volume of related tumors,such as non-small cell lung cancer,liver cancer and renal cell cancer.It is of great importance to accurately estimate the tumor weight,pathological volume of the tumor through the imaging volume of the tumor in clinical practice.MethodsIn this study,we chose 99 cancer patients who underwent surgery in Shandong provincial hospital from April 2017 to February 2018.In these cancer patients,there are 45 cases of lung cancer,18 cases of liver cancer and 36 cases of renal cell cancer.All of the clinical data were collected.Tumor body was collected after the resection surgery.The specimens were cleaned with aseptic saline to remove the blood and unrelated tissues.Tumor weight was collected with electronic balance,and the pathological volume of tumor was measured.Correlation analysis of tumor pathology volume and imaging volume using Pearson analysis.The correlation between tumor weight and pathological volume and imaging volume was also analyzed by Pearson method.The correlation between the tumor pathological volume and the average CT or MR imaging volume was compared by paired T test.ResultsThe average weight of tumor in lung cancer is 20.87±22.02g(0.95-80.13 g),liver cancer is 29.38±33.58g(3.58-108.60 g),renal cell cancer is 12.76±9.73g(3.64-69.59 g).The average CT or MR imaging volume in 99 patients are as follows: lung cancer of 18.92±19.49 mL(0.97-56.74 ml),liver cancer of 22.52±22.72mL(3.64-69.59ml),renal cell cancer of 26.918±18.419mL(6.79-53.66 ml).The average pathological volume in 99 patients are as follows: lung cancer of 20.369±21.92 mL(0.80-85.60 ml),liver cancer of 28.186±32.0 64mL(3.50-100.00 ml),renal cell cancer of 12.052±9.418mL(1.80-33.20 ml.Statistic analysis results indicated that there was no significant difference between the pathological volume and the CT or MR imaging volume whether in lung cancer(t=1.182,p=0.245)or liver cancer(t=1.74,p=0.105).However,the CT or MR imaging volume is much larger than the pathological volume in renal cell cancer(t =-5.88,p < 0.01).Stratified analysis of pathological types showed that there was a significant difference in the tumor weight,imaging volume and pathological volume of invasive adenocarcinoma and squamous cell carcinoma.There is no significant difference between imaging volume and pathological volume in hepatocellular carcinoma and hepatobiliary cell carcinoma.The imaging volume is larger than pathological volume in hyaline cell carcinoma and malignant cell carcinoma.Correlation analysis showed that the CT or MR imaging volume is highly correlated with that of pathological volume in lung cancer,liver cancer and renal cell cancer(r=0.940,0.958,0.883,respectively).In patient with lung cancer,liver cancer and renal cell carcinoma,it showed a highly positive correlation between the tumor weight with pathological volume(r=0.998,0.999,0.991),and the imaging volume(r=0.951,0.956,0.902).ConclusionsIn this study,we found that tumor weight showed a positive correlation with CT imaging volume and pathological volume in patients with lung cancer,liver cancer and renal cell cancer.There is no significant difference between CT imaging volume and pathological volume in patients with lung cancer.Correlation analysis showed that CT imaging volume and pathological volume showed a positive correlation,which we concluded that CT imaging volume could accurately assess the pathological volume of lung cancer patients to a certain extent.Similar results were obtained in patients with liver cancer.In liver cancer patients,the CT or MR imaging volume and pathological volume showed no significant difference,which meant that CT imaging volume could assess the pathological volume of liver cancer patients properly.However,it comes different in renal cancer patients.It showed a significant difference in CT or MR imaging volume and pathological volume in renal cancer patients.A highly positive correlation was found in CT or MR imaging volume and pathological volume.The CT imaging volume overestimated the pathological volume of the renal cell cancer to some extent.Clinically,the correlation between the CT imaging volume of the tumor and the pathological volume may have a certain effect on preoperative clinical decision and prognostic judgment of clinicians,In particular,the precise minimally invasive treatment based on thermal ablation has certain reference significance in ablation planning and the formulation of relevant ablation parameters. |
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