Predictive Value Of Tumor Vessel Density From Enhanced Spiral CT Scan For The Malignancy Of Small Intestinal Stromal Tumors

Background:With the development of modern science and technology,clinical medicine,more and more with the help of a multidisciplinary cooperation between.Modern medical diagnosis and treatment of the ideas and methods are also changing.Under this background,the surgery clinical treatment can be more with the aid of computer processing power of big data and the related clinical information.64 row spiral CT enhanced scan in each department of general application,makes use of computer to the 3 d reconstruction,image information more clearly shows the location of the lesions,the relationship with the adjacent organs,lesion blood supply information,such as the surgeons plan formulation,intraoperative navigation and positioning provides an important basis.At this point,will enhance preoperative CT three dimensional reconstruction of vascular density technique is applied to small intestinal stromal tumor malignant degree judgment,to estimate tumor pathology condition before the surgery,the treatment plan formulation and operation plan formulation,operation method and the resection range has important guiding significance.This article will combine the actual clinical data,this paper discusses preoperative enhancement CT three-dimensional reconstruction of vascular density technology forecasting value of small intestinal stromal tumor malignant degree.Objective:Through collecting the clinical data of clinical comparison analysis,to enhance preoperative CT three-dimensional reconstruction of vascular density prediction cases of small intestinal stromal tumor malignant degree value rationality analysis.Methods:Through retrospective selection between September 2015 and September 2015 the fellowship at jilin university hospital during gastrointestinal colorectal surgery anus line of small intestinal stromal tumor surgery patients.Into the group of patients with no history of abdominal surgery,previous preoperative use of Lightspeed VCT 64 layer spiral CT machine abdominal enhanced CT scan,and use it with AW4.4 post processing platform of the image processing to obtain small intestinal stromal tumor vascular three-dimensional images.The above image in high resolution color pathological graphic analysis system into two-dimensional image,and then measured value small intestinal stromal tumor vascular density(tumor vessel density,TVD)values.Take three different horizons as a fixed reference area,in the private area proportion of tumor blood vessels.Take three measuring average as tumor TVD values.Preoperative adjust body state can tolerate surgery,postoperative pathology of small intestinal stromal tumor.Cases in group a total of 25 cases,of which the Benign Small intestinal Stromal tumors(Benign Small bowel Stromal tumors,BSS)cases,9 cases of Malignant Potential in Small intestinal Stromal tumor(in all Malignant Potential Small bowel Stromal tumors,UMPSS)8 cases,Malignant Small intestinal Stromal tumors(Malignant Small bowel Stromal tumors,MSS)8 cases.Another postoperative pathological immunohistochemical expression of Ki-67 for evaluation of small intestinal stromal tumor malignant degree of another index.Results:1.BMS group TVD average value is 0.028,in three groups.MSS TVD values mean value of 0.073,largest of three groups.PMUSS group of TVD average value is 0.039.BMS group compared with the other two groups(P < 0.05,PMUSS group compared with MSS group(P < 0.05.Statistically significant difference between three groups.And the value of the TVD and tumor malignant degree into positive correlation.2.All the groups of cases of postoperative pathologic immuno histochemical Ki-67 is shown as: Ki-67 positive for 17 cases,negative for 8 cases of Ki-67.Positive cases of TVD average value is 0.054,the negative cases TVD average value is 0.028.Positive cases TVD average higher than the negative case,and the value of the TVD and small intestinal stromal tumor malignant degree into positive correlation.Conclusion:64 row of enhanced CT three-dimensional reconstruction of vascular density technology TVD value measured by the prediction of small intestinal stromal tumor malignant degree,thus for preoperative assessment of small intestinal stromal tumor pathological state to provide the reference.