The Curative Effect Of Analgesic Sedation After Moderate Brain Injury

Objective: To provides the basis for clinician’s choice of sedation plan and the basic data for similar sedation research by analyzing the difference of curative effect for different sedation depth in moderate craniocerebral injury.Methods: A retrospective analysis of 63 patients with moderate craniocerebral injury treated by neurosurgery from March 2016 to September 2017 was conducted.According to the depth of sedation received in NICU,they were divided into the deep sedation group and the shallow sedation group.They used RASS sedation score to make sedation assessment.Patients with score of-3~-4 were included in the deep sedation group,a score of 0~2 was taken into the shallow sedation group.33 cases were collected in the deep sedation group and 30 cases in the shallow sedation group.The postoperative data including mechanical ventilation time,NICU hospitalization days,acquired pneumonia,ICU delirium,acquired myasthenia,deep venous thrombosis,rebleeding and death of the two groups were collected.The results were statistically analyzed and the difference of curative effect was found..Results: The statistical results of the two groups showed a significant difference in mechanical ventilation time and NICU hospitalization days between the two groups(P<0.05).In the related complications,The data of acquired pneumonia and ICU delirium were statistically different(P<0.05),There was no significant difference between the two groups in the data on acquired myasthenia,deep venous thrombosis,secondary bleeding and death(P> 0.05).Conclusion: Compared with deep sedation,shallow sedation after moderate craniocerebral injury can significantly shorten mechanical ventilation time and NICU hospitalization days,reduce the incidence of complications such as acquired pneumonia and ICU delirium,and not increase the incidence of accidents such as secondary bleeding.