Effects Of High-flow Nasal Cannula Oxygen Therapy On The Anesthesia Of Colonic Or Rectal Endoscopic Submucosal Dissection Operations

Objective To explore the clinical effects of High-flow nasal cannula oxygen therapy on the anesthesia of gastrointestinal Endoscopic Submucosal Dissection operations.Methods Fifty-four patients undergonging colonic or rectal Endoscopic Submucosal Dissection operation were randomly divided into two groups.The patients in group A received High-flow nasal cannula oxygen therapy,and in group B given the coventional oxygen therapy.Monitor and record Sp O2,mean blood press(MAP),heart rate(HR),respiratory rate(RR)and the analysis of arterial blood gas(ABG)at different time points such as before induction of anesthesia,after induction of anesthesia,before operation,during operantion and after operation.Meanwhile,body movement during operantion,respiratory depression scale,also the anesthesia effect were recorded.Results Two groups were similar in having lower MAP and HR after induction of anesthesia(P<0.05).But they had no significant differences in MAP and HR at the same time point(P>0.05).Patients in group A were more comfortable,keeping breath and hemodynamic stable.The result of arterial blood gas(ABG),were significantly better than the group B(P<0.01),Pa O2 were higher(P<0.05)and Pa CO2 were lower(P<0.05).But side effects especially respiratory depression were less.The patients were pleased with the anesthesia.Conclusion The use of High-flow nasal cannula oxygen therapy in the anesthesia of colonic or rectal Endoscopic Submucosal Dissection operations is effective and safe.Patients feel comfortable,having a satisfied anesthesia.