| Objective The purpose of this study is to through the clinical symptoms,nutritional status in the group of patients with type 2 diabetic foot patients with relevant anthropometric and laboratory indicators,ankle brachial index(ABI)were observed,and the elderly nutrition risk index(GNRI)assessment of Qilian Decoction of four noble drugs on the nutritional status of patients with type 2 diabetic foot the patients of the intervention effect evaluation of the prognosis of diabetic foot,to provide new ideas and methods for the prevention and treatment of diabetic foot with traditional Chinese medicine.Methods In the 60 elderly patients with type 2 diabetic foot(grade 0)who would meet the criteria for inclusion in the group,stochastic contrasted single-blind study was used to divide the patients into two groups: the control group was treated with the standardized treatment of diabetes(education,sporting therapy,medical nutrition diet and rational application of hypoglycemic drugs).There are 30 cases in each group,three sessions for four weeks.Watching of clinical symptoms,the nutritional status of the patients before and after treatment of the relevant anthropometric and laboratory indicators,and the control of blood glucose,GNRI,ABI,and observe the safety index(liver and kidney function and urine routine,stool routine),using the SPSS software,t test,X~2 test,rank sum test.Result 1.clinical symptoms: TCM symptom score after treatment in treatment group was significantly different from that before treatment(P<0.05),which was also significantly different from that in control group(P<0.05).The total efficiency of TCM syndrome in the remedy tranche was 76.7%,and it was 44.8% in the other one.The total effective rate of Qilian Sijunzi Decoction was higher than that in the other tranche(P<0.05).2.anthropometric parameters: after treatment,the body mass index(BMI),triceps brachial fold thickness(TSF)and arm muscle circumference(AMC)of the two groups were significantly improved compared with those before remedy(P<0.05),and the efficacy of the remedy tranche was more better than that of the other tranche(P<0.05).3.GNRI : Before treatment,two groups of patients had different nutritional risks.After treatment,the nutritional risk of the two groups decreased,and the 7 patients with high nutritional risk in the treatment group were improved,and became the risk of low and middle nutritional risk in the two groups.The GNRI after treatment in the remedy tranche was markedly different from that of the other tranche(P<0.05).4.laboratory indicators: after treatment,the nutritional status and laboratory indexes of the two groups were improved(P<0.05).The patients in the treatment group the total protein,albumin,prealbumin,hemoglobin and red blood cells compared with the control group increased significantly(P<0.05),trace elements of calcium,iron,vitamin DT compared with the control group also increased significantly(P<0.05),retinol binding protein,triglyceride and total cholesterol,white blood cells,lymphocytes and high sensitivity CRP decreased(P<0.05),immunoglobulin Ig G,Ig M compared with the control group increased significantly(P<0.05).5.blood glucose index: two groups of patients with blood glucose were decreased after treatment(P<0.05),treatment group and control group after treatment,the fasting blood glucose and Hb A1 c were in the normal range(P>0.05),no significant difference were observed in the blood glucose index that is not affected.6.ankle brachial index: after treatment,the ankle brachial index of the patients improved in varying degrees,and the former is greater than the latter.(P<0.05).Conclusion the results of this study indicate that Qilian Four Gentlemen Decoction can significantly improve the nutritional status of diabetic foot(grade 0)patients and reduce the clinical symptoms of diabetic foot,and is safe and effective.Therefore,the application of Qilian Four Gentlemen Decoction to intervene the nutritional status of elderly patients with type 2 diabetic foot will provide new ideas and methods for the prevention and treatment of diabetic foot in the future. |
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