Application Of ¹⁸F-FDG PET/CT In The Study Of Remote Ischemic Postconditioning Improve Ischemia-reperfusion Injury In Patients With ST-segment Elevation Myocardial Infarction

Objective:To explore the role of fluoride-18-labeled deoxyglucose(¹⁸F-FDG)radionuclide positron emission tomography?PET/CT?in the treatment strategy and efficacy evaluation of ischemia-reperfusion injury?IRI?in patients with acute ST-segment elevation myocardial infarction after remote ischemia postconditioning?RIPostC?.Methods:The clinical data of 116 patients with acute ST-segment elevation myocardial infarction were retrospectively analyzed.51 patients who successfully underwent PET/CT examination in our department after treatment were enrolled in this study.According to the surgical methods,they were divided into two group.group A:primary percutaneous coronary intervention?PCI?;group B:PCI plusRIPostC,and The glucose metabolism and myocardial motion were determined by semiquantitative scoring.Results:There was no significant difference between the two groups in the 1?2?3?4?6?7?8?9?10 myocardial phases?P>0.05?.Compared with the control group,the proportion of myocardial viability in group B was significantly increased in the 5?11?12?13?14?15?16and 17 segments.The difference was statistically significant?P<0.05?.Compared with the LVEF values of PET-CT in two groups,the left ventricular function in group B was significantly improved compared with that in group A,the difference was statistically significant?P=0.017?.Conclusion:RIPerC can improve the left ventricular function in STEMI patients after operation.According to ¹⁸F-FDG PET/CT evaluation,RIPerC can significantly increase the survival of myocardial cells in infarcted area,and has a high value in therapeutic strategy and evaluation of curative effect.¹⁸F-FDG PET/CT myocardial metabolic imaging can evaluate myocardial viability very well.It has important clinical value in detecting the number of viable myocardium and can help clinicians to choose appropriate treatment.