| Objective:To analyze and compare the clinical effects of four surgical treatments for severe pelvic organ prolapse.Methods:From January 2017 to December 2017,12 cases of anterior and posterior vaginal wall repair(group A),71 cases of transvaginal pelvic floor reconstruction group B).37 cases of laparoscopic sacral fixation(group C)and 20 cases of vaginal closure(D group)were performed in the First Affiliated Hospital of Xinjiang Medical University.By retrospective analysis of the clinical data of the four groups,compared the perioperative indicators to evaluate the safety of surgery.The postoperative POP-Q score and quality of life questionnaire score(PFIQ-7.PFDI-20 score)were analyzed.and the objective efficacy.subjective satisfaction and sexual life of of the four groups were compared.Results:There were no significant differences in the general conditions among the four groups(P>0.05).The mean age of the D group was greatest(P<0.05).The operation time and hospitalization cost of group C were greater than those of the other three groups(P<0.05).There was no significant difference in other perioperative indicators between the four groups.The POP-Q scores of all anatomical indicators were significantly improved in each of the ABC groups after surgery(P<0.05).The POP-Q scores of each anatomical indicator point in group A were lower than those in group B and C(P<0.05).PFIQ-7 and PFDI-20 scores were significantly improved in the four groups at 1 month.6 months and 1 year after surgery(P<0.05);group A 6 months after surgery The PFDI-20 score was higher than the other three groups(P<0.05).The PFIQ-7 score was the highest in group A and the lowest in group C(P<0.05).The patients in group D had no sex before surger\.The satisfaction of sexual life in group C was higher than that in group AB(P<0.05).Conclusion:All four operations are effective surgical procedures for the treatment of POP.Laparoscopic patella fixation is more suitable for women with active sexual life and high quality of sexual life.Patients with low sexual life requirements and inability to tolerate prolonged surgery may use vaginal anterior wall repair or transvaginal pelvic floor reconstruction;For patients with severe prolapse who have a high age of asexual life,the curative effect of vaginal closure is positive,which can improve the quality of life of patients after surgery. |