Clinical Observation Of Light Fasting On Improving Abnormal Glucose And Lipid Metabolism In Obese Type2 Diabetes

Objective:To observe light fasting(selected for 1 day per week,500 kcal of very low calorie food on the day of light fasting),and the light-fasting diet of the remaining 6 days of diabetes diet for blood of overweight and obese patients with type 2 diabetes Biochemical indicators,including Fasting Plasma Glucose(FPG),2-hour postprandial blood glucose(2hPG),blood lipids(total cholesterol(TC),triglyceride(TG),low-density lipoprotein cholesterol(LDL-C),high Density lipoprotein cholesterol(HDL-C)and morphological indicators include the effects of body weight,body mass index(BMI),hip circumference,waist circumference,and derived waist-to-hip ratio.The data of physicochemical indexes and body morphological parameters of glycolipids before and after light fasting treatment were compared and analyzed,and the effectiveness of light fasting on the improvement of glucose and lipid metabolism in overweight and obese type 2 diabetic patients was evaluated.Methods: This clinical observation was performed by enrolling in the outpatient department of the Department of Endocrinology,Affiliated Hospital of Changchun University of Traditional Chinese Medicine,and the inpatients met the inclusion criteria.Type 2 diabetes with overweight and obesity 24kg/m2?BMI?32kg/m2,7%? Glycated hemoglobin ?8%,oral metformin hydrochloride as a basic treatment for type 2 diabetes patients.They were divided into treatment group and control group by random grouping.Treatment group(basic treatment + light fasting);control group(basic treatment).The non-light fasting days of the treatment group and the daily diet of the control group were formulated according to the Chinese Dietary Guidelines(2007)and the Chinese Type 2 Diabetes Prevention Guide 2013,see attached table.A total of 12 weeks of observation.Through the collection and comparison of the treatment group and the control group before and after treatment,the quantitative data of physicochemical examination of glycosphate and body morphological parameters were used to evaluate the efficacy of light fasting once a day.Results:1.After 12 weeks of treatment,fasting blood glucose,2 hours postprandial blood glucose,glycated hemoglobin HbAlc,total cholesterol(TC),high density lipoprotein cholesterol(HDL-C),The values ? ? of Low Density Lipoprotein Cholesterol(LDL-C)and Total Triglyceride(TG)were compared with those in the pre-treatment group.The physical and chemical examination values ? ? of the two groups before and after treatment were compared P<0.05,and the difference was statistically significant.It is indicated that both the treatment group and the control group can improve the above-mentioned values of the physicochemical examination of glycolipids.Fasting blood glucose,2 hours postprandial blood glucose,glycosylated hemoglobin HbAlc,total cholesterol(TC),high density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(HDL-C)The values of Low Density Lipoprotein Cholesterol,LDL-C)and Total Triglyceride(TG)were compared between the two groups(P<0.05).The difference was statistically significant,indicating that the treatment group was significantly better in improving the physical and chemical properties of the above physicochemical glycolipids.In the control group.2.After 12 weeks of treatment,the body morphological parameters(body weight,body mass index BMI,waist circumference,hip circumference,waist-to-hip ratio)of the two groups were different from those in the pre-treatment group,P<0.05,the difference was Statistical significance.It is indicated that both the treatment group and the control group can improve the body shape index values.The body morphological indexes(body weight,body mass index BMI,waist circumference,hip circumference,waist-to-hip ratio)of the two groups were compared between groups,P<0.05,the difference was statistically significant,indicating that the body shape index values ??were improved.In the treatment group,it was significantly better than the control group.Conclusion: Light fasting once a day may be fasting blood glucose,2 h postprandial blood glucose,blood lipids: Total Cholesterol(TC),High Density Lipoprotein Cholesterol(HDL)in overweight and obese patients with type 2 diabetes.-C),low density lipoprotein cholesterol(Low Density Lipoprotein Cholesterol,LDL-C),triglyceride(TG),body weight,body mass index BMI,waist circumference,hip circumference,waist-to-hip ratio havepositive effects.