Correlated Research Between Nonvalvular Atrial Fibrillation And The Ratio Of Peripheral White Blood Cells Count And Subtype

Objective: The purpose of the article aims to investigate the significance of systemic inflammatory response to nonvalvular atrial fibrillation(NVAF),by studying the connection among peripheral white blood cell count(WBC),neutrophil-lymphocyte ratio(NLR)and lymphocyte monocyte ratio(LMR),and the occurrence of NVAF,along with atrial remodeling.Methods: The sample size selected from the first affiliated hospital of Xinjiang medical university,who admitted in the heart center from June 2016 to June2018,including 233 patients with NVAF,and another 110 in the control group.Conducting a univariate analysis to assess statistically significant factors based on their general clinical data,laboratory examination,and echocardiographic data gathered.Besides,according to a multivariate Logistic regression to evaluate whether the factors have a significant influence on patients with NVAF.Furthermore,figuring out the correlation between the levels of WBC,LMR,and NLR with the indicators of the echocardiogram.Outcomes: The experimental group has all higher values in history of smoking,and history of Hypertension,and their fasting plasma glucose,NLR,and Left Atrial Diameter(LAD),and Left Ventricular Diameter(LVD)give greater amounts than the control group as well(p<0.05).Besides,Total Cholesterol,HDL-C,and left ventricular ejection fraction(LVEF)own a lower value(p<0.05)than the control group.For multivariate Logistic regression,it shows that history of Hypertension,and an increase in NLR and LAD could be risk factors for atrial fibrillation(AF).Moreover,the results of Spearman describe that the level of NLR significantly has a positive correlation with LAD(r=0.24,p<0.01).For LVEF,the level of NLR significantly owns a negative correlation with the indicator(r=-0.16,p<0.01).Conclusions: It could be identified that NLR is arisk factor for AF,which is correlated with the cardiac structural index of AF patients as well.Therefore,it is concluded that the assessment of NLR index has certain clinical value for the evaluation of atrial fibrillation.