Clinical Study Of Low-intensity Neuromuscular Rehabilitation Combined With Noninvasive Ventilation In The Treatment Of Chronic Obstructive Pulmonary Disease With Type Ⅱ Respiratory Failure

Objective The purpose of this study was to evaluate the clinical effect of low intens ity neuromuscular rehabilitation on COPD complicated with Ⅱ respiratory failure patie nts with non-invasive positive pressure ventilation to explore the improvement of the q uality of life,exerciseendurance,dyspnea and hospitalization time.Methods 86 cases of COPD complicated with Ⅱ respiratory failure patients used no n-invasive positive pressure ventilation were divided into the rehabilitation group and t he control group according to the random digital table method.during the time from Ja nuary 2018 to December 2018 year in the Department of respiration,traditional Chine se medical of ZhuJi.All of patients were treated with conventional medication and no n-invasive positive pressure ventilation.The rehabilitation group started the pulmonary rehabilitation training twice a day,it was including low intensity exercise training,and neuromuscular rehabilitation twice a day,it was including NEMS.After low intensity neuromuscular rehabilitation,the two aroups were comparedlincluding:arterial oxvgen pressure(PaO2),arterial blood pressure(PaCO2),lung function FEV1(FEV1%pred),F EV1/FVC,30 seconds chair sitting test(30-STS),modified British Medical Research Council(mMRC),chronic obstructive pulmonary disease test score(COPD assessment tes t,CAT),Quadriceps muscle strength and hospitalization time.Results 1.After the low intensity neuromuscular rehabilitation,there was no significant difference in Pa02、PaCO2、FEV1%pred、FEV1/FVC between the two groups(P>0.05).Compared with the control group,the times of 30-STS were significantly increased(the rehabilitation group:10.48±1.66 times,and the control group:9.23±1.25 times,P<0.05),the mMRC scores were significantly decreased(the rehabilitation group:1.73±0.51 scores,dan the control group:2.09±0.62 scores,P<0.05),the CAT scores of the rehabilitation group were significantly decreased(the rehabilitation group:13.40±2.28 scores,and the control group:15.03±2.96 scores,P<.05),Quadriceps muscle strength increased significantly(the rehabilitation group:Left quadriceps peak torque:76.36±3.74 Nm,Right quadriceps peak torque:75.78±4.26 Nm;and the control group:Left quadriceps peak torque:70.03±4.83 Nm.Right quadriceps peak torque:70.32±5.41 Nm;P<0.05),and the hospitalization times were shortened significantly(the rehabilitation group:10.81±2.34 days,and the control group:11.95±2.13 days,P<0.05)2.No serious adverse events occurred during the whole low intensity neuromuscular rehabilitationConclusion 1.The Low intensity neuromuscular rehabilitation can significantly improve the quality of life,increase exercise endurance,alleviate dyspnea symptoms and shorten the hospitalization time for the patients of COPD complicated with Ⅱ respiratory failure who had used non-invasive positive pressure ventilation during the hospitalization period2.Low-intensity neuromuscular rehabilitation is safe and feasible for non-invasive positive pressure ventilation in patients with COPD and Ⅱ respiratory failure.