Dioscorea Gold Cream For Patients With Chronic Obstructive Pulmonary Disease And Stable Lung Spleen Qi Deficiency Syndrome Immune Function

Objective:To investigate the effect of Dioscorea Gold Glucose on clinical efficacy and immune function in patients with chronic obstructive pulmonary disease with stable spleen qi deficiency syndrome.Methods:Seventy patients?aged 45-75 years old?were enrolled in the respiratory medicine clinic of Ruikang Hospital affiliated to Guangxi University of Traditional Chinese Medicine.They were admitted to the outpatient department of the Department of Respiratory Medicine of Guangxi University of Traditional Chinese Medicine and were eligible for the COPD stable phase of lung spleen qi deficiency and COPD.All patients were randomly divided into control group?35 cases?and treatment group?35 cases?according to the random number table.The control group was treated with Western medicine?Tiotropium bromide inhalation therapy?,and the treatment group was treated with the Chinese Academy of Respiratory Medicine on the basis of the treatment of the control group.The drug composition:yam 540g,Codonopsis 300g,Fried Atractylodes 108g,Poria cocos 200g,Zhigancao 200g,White lentils 180g,Rehmannia glutinosa 180g,Angelica 180g,White peony 108g,Chuanxiong 108g,Jianqu 180g,Jujube200g,Bitter almond 108g,Guizhi 100g,Bupleurum 90g,windproof 200g,dried ginger 54g,white peony 36g,platycodon 200g,Ophiopogon japonicus108g,Ejiao 200g?Suihua?,dried tangerine peel 200g;Accessories:maltose300g,rice wine 100ml;this side 1 material for 30 days,by hospital drug development The center made about 1200g of cream,each time taking 20g,warm water,2 times a day,1 time each morning and evening.The two groups of treatments were 2 months.Observe the TCM syndrome scores of the two groups before and after treatment.Pulmonary function forced vital capacity?FVC?,forced expiratory volume in 1 second?FEV₁?,forced expiratory volume in 1 second and forced vital capacity ratio?FEV₁/FVC?,immunological indicators of T lymphocytes Subgroups of CD3⁺,CD4⁺,CD8⁺,CD4⁺/CD8⁺changes.Results:1.Comparison of TCM syndrome scores and clinical efficacy between the two groups:the scores of cough,cough,shortness of breath and wheezing in the two groups were lower than those before treatment,the difference was statistically significant?P<0.05?,and the treatment group was superior to the control group.The difference was statistically significant?P<0.05?.In terms of fatigue and spontaneous sweating,there was no significant change in the control group before and after treatment,and there was no statistical significance?P>0.05?.The treatment group could be significantly improved after treatment,and the difference was statistically significant ?P<0.05?.The total effective rate was 97.10%in the treatment group and 88.50%in the control group.The treatment group was better than the control group,and the difference was statistically significant?P<0.05?.2.There were no significant changes in FVC,FEV₁,and FEV₁/FVC%before and after treatment in the control group,no statistical significance?P>0.05?.The treatment group FVC,FEV₁ improved before treatment,the difference Statistically significant?P<0.05?.After treatment,the improvement of FVC in the treatment group was better than that in the control group,and the difference was statistically significant?P>0.05?.3.Comparison of immunological indicators.There were no significant changes in the levels of CD3⁺,CD4⁺,CD8⁺,CD4⁺/CD8⁺in peripheral blood Tlymphocyte subsets after treatment?P>0.05?.After treatment in the treatment group,peripheral blood tlymphocyte subsets CD3⁺,CD4⁺increased,CD4⁺/CD8⁺ratio increased,the difference was statistically significant?P<0.05?,after treatment two Compared with the control group,the difference was statistically significant?P<0.05?.Conclusion:Dioscorea gold cream combined with tiotropium bromide inhalation in the treatment of chronic obstructive pulmonary disease patients with stable lung spleen qi deficiency is better than western medicine alone,which can significantly improve the symptoms of cough,cough,shortness of breath and wheezing,especially the improvement of fatigue.Self-sweat symptoms,and can enhance the patient's cellular immune function.