| Objective:①Verify accuracy based on msct 3D pancreas volume measurement.②Statistics on the size and variation of pv in normal Han population and the influencing factors of pv size③Analyze the differences between PV,PVI,PD,BMI and biochemical indicators in normal people and t2dm patients,Summarize the correlation of various indicators for the diagnosis of t2dm.Materials and Method:Materials:①Ten pancreas models of different sizes and shapes were made out of rubberized clay.The model volume was measured by the drainage method,the three-dimensional method and the integral method,and the consistency of the measurement results of different measurement methods was compared.·②Retrospective analysis of 615 patients who received plain and enhanced abdominal CT scan and enhanced CT scan in radiology department of our hospital from May 2017 to June 2018 were divided into normal group and T2DM group.In the normal group,there were 519 cases,including 262 males and 257 females,aged from 18 to 89 years,with an average of 53.01±13.2 years.In the T2DM group,there were 96 cases,including 53 males and 43 females,aged from 29 to 82 years,with an average of 64.16±9.95 years.Method:①Variance analysis of random block design was used to test the consistency of the results of pancreatic volume measurement by different methods.②By age grouping,statistics of human pv,pvi,spleen-pancreatic density difference and pancreatic margin with age increase.③The correlation between the sex,age,weight,height,body mass index(BMI),body surface area and the size of pancreas was studied by independent sample T test and linear regression.④Age,weight,height,volume of pancreas(PV),ratio of pancreas(PVI)and density of pancreas(PD)were studied by binary logistic regression.Results:①There was good consistency between the volume of the pancreatic model measured by drainage method,three-dimensional method and integral method,and there was statistical difference between the three methods(F=1.589,P=0.232).The measurement results of three-dimensional method and drainage method are highly consistent(t=1.382,P=0.20).②The normal male PV and PVI gradually increased with age,reached the peak at 40 to 49 years old,and gradually decreased after 50 years old,Normal women PV,PVI reach a peak in the 30 to 39 years old,and gradually decline after 40 years old.③The spleen-pancreatic density difference and pancreatic marginal rating of the normal population gradually increase with age.④The PV in the normal male group(78.3±17.05)was larger than that in the female group(61.76±12.8),and the difference between the two was statistically significant(F=155.83,P<0.001).The PVI in the normal male group(40.69±7.56)was larger than that in the female group(36.44±6.84),and the difference between the two was statistically significant(F=45.02,P<0.001).⑤The size of PV was correlated with BSA(P<0.001)and PD(P<0.001)in normal group and is not correlated with BMI(P=0.688).⑥T-test analysis of independent samples showed that PV(P<0.001),PVI(P<0.001),PD(P<0.001),Dense density of spleen and pancreas(P<0.001),Pancreatic edge(P<0.001),BMI(P=0.02),family history of diabetes(P=0.01)and HDL-C(P=0.004)were significantly different between diabetic group and normal group.⑦The binary logistic regression analysis showed that male PVI(P<0.001),family history of diabetes(P=0.003),Dense density of spleen and pancreas(P=0.035)and pancreatic head width(P=0.011)were correlated with T2DM.Female PVI(P=0.002),Dense density of spleen and pancreas(P=0.008),HDL-C(P=0.044)and pancreatic head width(P=0.015)were correlated with T2DM.Conclusion:①Application of MSCT scanning to PV Measurement method is accurate and reliable.②The changes of PV and PVI were curvilinear with age,Women reach the peak age group earlier than men.③PV size has gender differences,The PV and PVI in the normal group were higher than those in the female.④PV is positively correlated with BSA.⑤Compared with the normal group,the PV and PVI of T2DM patients decreased significantly,and the fat infiltration was significant. |
PDF Full Text Request