| OBJECTIVE:Noninvasive percutaneous monitoring and end-expiratory co2 partial pressure(Pet CO2)monitoring were performed on premature infants requiring mechanical assisted ventilation in hospital,so as to clarify their clinical application value.METHODS: Thirty-one premature infants who underwent mechanical ventilation in the neonatology department of Anqing Hospital Affiliated To Anhui Medical University from 2017-12-1 to 2018-7-1 were enrolled,and blood gas analysis was performed in 75 cases.Non-invasive percutaneous monitoring using the Danish Thunder Percutaneous Oxygen/Carbon Dioxide Analyzer(TCM 400)requires calibration of the machine prior to monitoring.The end-tidal carbon dioxide partial pressure monitoring was performed using the Philips Intelli Vue MP40 and the specific values of the end-tidal carbon dioxide partial pressure were recorded after the non-invasive percutaneous monitoring readings were stabilized.Blood gas analysis was performed using the US GEM Premler 3000 blood gas analyzer,blood gas analysis of the radial or femoral artery was performed,and the blood sampling time was stabilized after the non-invasive percutaneous monitor and the end-tidal carbon dioxide partial pressure monitor were stable.The measurement data were expressed as mean±standard deviation(x ±s).The correlation between Pet CO2 and Tc PCO2 and Pa CO2 and the correlation between Tc PO2 and Pa O2 were analyzed by Pearson’s linear regression analysis.The correlation coefficient was calculated.P<0.05 was considered statistically significant.Result:Comparing end-tidal carbon dioxide partial pressure(Pet CO2)with the partial pressure of carbon dioxide in blood gas analysis: the relevant data in each group are in a normal distribution,and when the partial pressure of carbon dioxide in blood gas is taken as the independent variable and the partial pressure of carbon dioxide at the end of expiration is taken as the dependent variable to make the scatter plot,we find that as the independent variable increases,the dependent variable also increases,and the trend of change is the same.The scatter pattern is approximately linear,Therefore,the Pco2 at the end of expiratory period was linearly correlated with the Pco2 in the blood gas analysis,and the correlation coefficient was(r=0.73,P<0.01),indicating a statistical significance between the two.2,Comparison of pco2 with pco2 in blood gas analysis :We can also see from the scatter plot that there is a linear relationship between pco2 and pco2 in blood gas analysis.,and there is also a positive linear correlation between pco2 and pco2,and The correlation coefficient is(r=0.87,p<0.01),which is also statistically significant.3.Comparison of oxygen partial pressure between transcutaneous oxygen partial pressure and blood gas analysis :The scatter plot also showed a linear positive correlation between the two,and the correlation coefficient was(r=0.61,p<0.01),which was also statistically significant.4.Comparison of end-tidal carbon dioxide partial pressure,transcutaneous carbon dioxide partial pressure,transcutaneous oxygen partial pressure and blood gas analysis in oxygen partial pressure and carbon dioxide analysis: In the comparison of the three,Percutaneous carbon dioxide partial pressure and Pco2 in blood gas analysis have the highest correlation coefficient(r=0.87,and the correlation coefficient between them is r=0.73,r=0.61),so we can get all the indicators we tested.There is a significant correlation between the percutaneous carbon dioxide partial pressure and the partial pressure of carbon dioxide in the blood gas analysis.In Conclusion:Regardless of non-invasive percutaneous monitoring or end-tidal carbon dioxide partial pressure monitoring,there is a certain correlation between the number of indicators monitored and the number of indicators for blood gas analysis,but both have certain limitations.Compared with blood gas analysis,each has its own Advantages and disadvantages,it can not completely replace blood gas analysis in the clinical,blood gas analysis is still the "gold standard" to understand oxygen partial pressure and carbon dioxide partial pressure,non-invasive percutaneous monitoring and end-tidal carbon dioxide partial pressure monitoring can be used as a blood gas analysis An auxiliary tool can help clinicians to continuously observe changes in oxygen partial pressure and carbon dioxide partial pressure in children. |
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