Effect Of Laparoscopic Cholecystectomy In The Treatment Of Mild Acute Biliary Pancreatitis

Objective:To compare the effect of laparoscopic cholecystectomy(LC)and delayed LC(4-6 weeks after inflammation control)in patients with mild acute biliary pancreatitis(MABP),and to explore the feasibility and safety of LC in the early stage.Methods:We collected 74 patients with biliary pancreatitis treated with LC in our hospital from January 2014-December 2018,and the patients who met the MABP diagnosis and were treated for the first time were included in the experimental group,a total of46 cases.In the past,patients with a history of MABP and one or more hospitalize-ations were treated with LC surgery for a delay,followed by a total of 28 patients.The factors of operation time,postoperative biochemical index,total hospitaliza tio n time,hospitali-zation cost were compared.Results:The operation time,hospitalization days and total cost of the experimental group were 55.14(±17.36),11.38(±3.18)and 23.5(±5.8)thousand,respectively.The operation time,hospitalization days and total cost of the control group were 57.47(±15.14),14.47(±5.09)and 31.8(±7.5)thousand,respectively.There was no signific-ant difference in operation time between the two groups(P>0.05),and the difference in hospitalization days and total cost was statistically significant(P<0.05).The indexes of serum amylase,urinary amylase,ALT,AST and alkaline phosphatase were102.36(±25.14),332.17(±65.13),51.35(±3.18),57.45(±5.19),147.57(±17.61)in the experimental group and 95.41(±22.58),217.25(±66.34),58.43(±4.05),57.44(±3.19)and 141.29(±20.62)in the control group one day after operation,respectively.There were significant differences between the two groups(P < 0.05).Four days after operation in the experimental group were 83.85(±9.74),255.98(±30.24),45.93(±2.18),48.18(±3.29),132.34(±16.87),and in the control group,79.67(±9.82),197.18(±33.62),43.13(±3.17),44.47(±4.19),130.58(±14.55),respectively.There was no significant difference between the two groups(P > 0.05).Conclusion:Patients with MABP can effectively exclude the common bile duct stones after the auxiliary examination.It is feasible and safe to perform LC treatment during the first hospitalization of the patients.It can effectively reduce the recurrence and reduce the hospitalization time while achieving the therapeutic effect.Reduce patient hospitalization costs.