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The Correlation Between Knee Osteoarthritis And Osteoporosis Based On Medical Record Analysis

Posted on:2020-03-05Degree:MasterType:Thesis
Country:ChinaCandidate:X S ChangFull Text:PDF
GTID:2404330575956807Subject:Fractures of TCM science
Abstract/Summary:PDF Full Text Request
Osteoarthritis(KOA)with osteoporosis(OP)in terms of gender,age,duration of disease,and X-ray staging;(2)To investigate the clinical efficacy of anti-osteoporosis in patients with knee osteoarthritis and osteoporosis.2.Retrospective study of imaging:(1)Analysis of differences in X-ray,CT and MRI between patients with knee osteoarthritis and those with osteoporosis;(2)To investigate the clinical efficacy of anti-osteoporosis in patients with knee osteoarthritis and osteoporosis.Methods:1.Retrospective study of medical records:Through the collection of the hospital's medical records from October 2011 to October 2017,the first diagnosis of patients with knee osteoarthritis was 1811 cases.According to the relevant inclusion and exclusion criteria,1573 cases were excluded,including medical records.In 238 patients,information such as the patient's name,gender,age,duration of illness,medication status,clinical symptoms,and treatment status were collected.Patients were divided into two groups based on whether or not anti-osteoporosis drugs were used.Group A is the basic treatment for knee osteoarthritis combined with anti-bone.For patients with osteoporosis,group B is the basic treatment for knee osteoarthritis.The symptom score,HSS score,and VAS score before and after treatment were compared between the two groups.The therapeutic effects of the two groups were compared.2.Retrospective study of imaging:A total of 608 patients with knee osteoarthritis(KOA)were diagnosed in the hospital's medical records from October 2015 to October 2017.According to the relevant exclusion criteria,the patient's medical history is excluded.All patients underwent x-ray,CT,and MRI,including 141.According to the diagnosis of osteoporosis,group A was diagnosed with 55 cases of osteoporosis,and the group B was 86 cases without osteoporosis diagnosis.The two groups were analyzed in the joints.Differences in gap,bone changes,free body,cartilage changes,synovial changes,meniscus degeneration,joint effusion,subchondral bone fractures,bone marrow edema,and X-ray,CT,MRI Similarities and differences between the two.Results:1.Retrospective study of medical records:(1)Quantitative scores of symptom scores: There was no statistically significant difference in the quantitative score of symptom grading on the day of admission(P>0.05),compared with the two groups before treatment,the quantitative score of symptom classification decreased,there were significant statistical differences(P<0.01),and the effect of group A was better than that of group B after treatment,and the difference was statistically significant(P<0.05).(2)HSS score: At the time of admission,the HSS scores of the two groups were compared,the difference was not statistically significant(P>0.05);the two groups were treated with the HSS score before treatment,and the treatment was effective.The difference was statistically significant(Comparison within the group,P <0.01);after treatment,the improvement of pain,activity and reduction in HSS scores in group A was better than that in group B,the difference was statistically significant(P<0.05).However,in terms of function,muscle strength,flexion deformity and stability improvement in HSS scores,the effects of group A and group B were comparable,and the difference was not statistically significant(P>0.05).(3)VAS scores: On the day of admission,there was no significant difference in the VAS scores between the two groups(P > 0.05),but the VAS scores in the two groups were significantly lower than those before admission(P < 0.01).After hospitalization,the effect of group A was better than that of group B(P < 0.01).The VAS score of group A was better than that of group B(P < 0.05).(4)Efficacy evaluation: After treatment,the curative effect of the two groups was better than that of the B group,and the difference was statistically significant(P<0.01).2.Retrospective study of imaging:(1)X-line comparison: In the joint space,bone,cartilage,meniscus and the symptoms of subchondral microfracture,the symptoms in group A were more than those in group B(P < 0.05),but in isolated synovium,the change of synovial membrane was significantly higher than that in group B(P < 0.05).There was no significant difference between group A and group B in joint effusion and bone marrow edema(P > 0.05).(2)CT comparison: In the two groups of patients with joint space changes,bone changes,cartilage changes,synovial changes,meniscus degeneration,subchondral microfracture,the detection rate of group A was better than group B,the difference was statistically significant(P <0.05),but in the free body,joint cavity effusion,bone marrow cavity bone marrow edema,there was no difference between the A group and the B group,the difference was not statistically significant(P>0.05).(3)MRI comparison: In terms of joint space changes,bone changes,cartilage changes,synovial changes,meniscus degeneration,subchondral microfractures and bone marrow edema,the symptoms in group A were significantly higher than those in group B(P < 0.05).However,there was no significant difference between group A and group B(P > 0.05)in the aspect of effusion of joint cavity and free body(P >0.05),and there was no significant difference between group A and B(P > 0.05).(4)X-ray,CT,MRI comparison: X-ray,CT,MRI showed no significant difference in the detection rate of joint space change(P>0.05);the detection rate of bone change MRI was higher than X-ray(P<0.05),X-ray and CT and CT and MRI were not statistically significant(P>0.05);free body detection rate X-ray and CT were higher than MRI(P<0.05),X-ray and CT were not statistically significant.Significance(P>0.05);cartilage changes,synovial changes,meniscus changes,MRI detection rate is better than CT,CT detection rate was higher than X-ray(P<0.05);joint cavity effusion CT and MRI examination rate There was no statistical difference(P>0.05),but CT and MRI were significantly better than X-ray(P<0.05).MRI of subchondral bone fracture and bone marrow edema was significantly better than CT and MRI (P<0.05).Conclusion:1.Clinical knee osteoarthritis with osteoporosis patients,combined with anti-osteoporosis drug intervention,can effectively reduce patient pain,improve patient function,improve the efficacy of diagnosis and treatment,it is recommended that in the course of clinical diagnosis and treatment,knee osteoarthritis with osteoporosis patients should be combined with anti-osteoporosis treatment.2.In patients with knee osteoarthritis and osteoporosis,the detection rate on X-ray,CT and MRI is higher than that in patients with knee osteoarthritis.The treatment of patients with knee osteoarthritis and osteoporosis should pay attention to the joint anti-bone.Treatment of loose drugs.3.X-ray,CT,MRI for knee joint examination,all three imaging have diagnostic value,but each has its own advantages,clinical impact examination should complement each other.
Keywords/Search Tags:Knee osteoarthritis, Osteoporosis, Retrospective study, Anti-osteoporosis treatment, Film degree exam
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