The Effects Of High-intensity Intermittent And Moderate-intensity Continuous Training On Vascular Endothelial Function In Patients With Coronary Heart Disease:meta-analysis

Objective To evaluate the effects of two different exercise modes,high-intensity interval training(HIIT)and medium-intensity continuous training(MICT),on vascular endothelial function in patients with coronary heart disease.Methods The China National Knowledge Infrastructure,VIP Database,Wanfang Database,Cochrane Library,Pubmed,and Embase were searched for randomized controlled trials of vascular endothelial function changes in patients with coronary heart disease under different training modes.The observed indicators: brachial artery endothelium-dependent blood flow-mediated dilation(FMD).The intervention time should be more than 2weeks.After evaluating the quality of the selected literature,extracting the literature data,and meta-analysis was performed using RevMan software(version 5.3)which was provided by Cochrane System Intervention Evaluation Manual.Results A total of 535 relevant literatures were selected according tothe inclusion and exclusion criteria,among which 5 studies were consistent with the inclusion and exclusion criteria,with a total of 509 patients.According to the heterogeneity results: I2=0%(I2< 50%),P=0.62(P>0.1),X2=2.65,no heterogeneity,the fixed-effect model was used for analysis.There was no significant difference in brachial artery FMD between HIIT group(n=236)and MICT group(n=273),95% confidence interval [-0.46,0.69(Z=0.39,P=0.70),MD=0.11.Conclusion There was no difference between the two exercise patterns in improving vascular endothelial function in patients with CHD.