Analysis Of The Curative Effect Of High Frequency Electrocauterization And Implantation Of Hepatic Arterial Chemotherapy-Pump In The Treatment Of Multiple Hepatic Metastatic Carcinoma Of Colorectal Cancer

With the continuous increase of living environment and social pressure,the incidence of malignant tumors increases year by year.Colorectal cancer is the third largest malignant tumor in the world,and there are more than 1.2 million new cases and 600,000 deaths globally every year.And in our country,colorectal cancer is the most common digestive tract malignant tumors,the incidence is about 31.39/10,with the change of the people’s living habits,ShiWuPu,its incidence is obviously rising trend.Colorectal cancer liver blood line transfer part of the common,and whether the liver metastatic,is one of the main factors affecting survival and prognosis of liver metastatic colorectal cancer(colorectal liver metastases,CRLM)is the leading cause of death in patients with colorectal cancer,untreated colorectal multiple hepatic metastatic carcinoma median survival period less than 12 months,5 years survival rates c ose to zero.At present,liver metastasis of colorectal cancer can be divided into simultaneous liver metastasis and heterogeneous liver metastasis.According to the 2018 international guidelines and China s guidelines for diagnosis and comprehensive treatment of colorectal cancer with liver metastases,synchronous liver metastases refer to liver metastases found before or at the time of diagnosis of colorectal cancer.Liver metastases after radical resection of colorectal cancer are called metachronous liver metastases.And surgical resection is the only cure for colorectal cancer liver metastatic carcinoma,but less than for heterochrony liver metastatic carcinoma,and hepatic metastatic carcinoma has a unique advantage can be a period of surgical removal of the primary lesion and lier cancer stove,but it can benefit patients with only a few of the operation,the vast majority(80.0%～90.0%)of liver metastases are unable to get radical excision.Therefore,timely diagnosis of colorectal cancer can reduce the occurrence of liver metastasis,as well as the occurrence of liver metastatic cancer in a timely and accurate understanding of the status of patients with liver metastatic cancer,can improve the survival rate of patients.The treatment of liver metastases from colorectal cancer is divided into surgical treatment and non-surgical treatment.Surgical treatment according to whether the preoperative application of chemotherapy drugs and other means can be divided into direct surgery,neoadjuvant chemotherapy after surgical resection,temporarily unresectable liver metastatic transformation therapy,through various technical means is still not completely resectable state called permanent unresectable colorectal cancer liver metastasis.Therefore,accurate preoperative assessment of the status of primary lesions and liver metastatic carcinoma and the selection of preoperative treatment methods can greatly reduce the perioperative mortality of patients and improve the long-term postoperative survival rate.In this paper,the efficacy of high-frequency electrocauterization and implantation of hepatic artery chemotherapy pump in patients with multiple liver metastases of unresectable colorectal cancer was analyzed,and the postoperative survival period of the patients was discussed.ObjectiveObjective to investigate the efficacy of high frequency electrocauterizationand implantation of hepatic arterial chemotherapy pump in patients with multiple liver metastases of unresectable colorectal cancer and discuss the postoperative survival of the patientsMethodsA retrospective analysis of 46 patients with colorectal cancer with multiple hepatic metastases from colorectal cancer admitted to the Department of General Surgery,Second Affiliated Hospital of Shenyang Medical College from September 2012 to June 2018 was included in the study.A controlled study was performed for the surgical and non-surgical groups.The surgical group treated patients with colorectal cancer with liver metastases by corresponding radical resection of colorectal cancer,high-frequency electrocautery,liver metastases,and hepatic arterial chemotherapy.Non-surgical group received systemic chemotherapy.ResultsThe application of high-frequency electrosurgical cautery for hepatic metastatic cancer and hepatic artery implantation chemotherapy for active treatment of colorectal carcinoma have positive effects compared with non-surgical treatment,which can significantly improve the curative effect and improve the survival rate of patients.However,the causes of death of the patients in the operation group were basically no effect of injection chemotherapy and embolization drugs on liver metastasis,leading to the development of liver metastasis.Both the patients in the operation group and the non-operation group died of liver failure.Postoperative survival rates at 1,2,and 3 years were statistically different between the two groups.The 5-year survival rate of patients with liver metastasis of colorectal cancer in both groups was 0%.ConclusionThe majority of patients in the non-surgical group died within 1 year,while the survival period of patients with metastatic carcinoma of colorectal cancer was almost more than 1 year with the application of high-frequency electrosurgical cautery and hepatic artery implantation chemotherapy.Compared with non-surgical treatment,the survival rate of patients was significantly improved.Patients in both the surgical and non-surgical groups died from the development of metastatic cancer,leading to liver failure.The postoperative survival rates of the two groups were statistically different.The 4-and 5-year survival rates were 0%in both groups.