Analysis Of Clinical Efficacy Of Different Hemostasis Methods In Patients With Cervical Cold Knife Conization

Purpose:In this paper,we retrospectively studied the different clinical efficacy of different hemostasis methods in patients with cervical cold knife conization,and provided some references for clinical work.Method:289 cases of patients with cervical high-grade squamous intraepithelial lesion who underwent cervical cold knife conization in the Second Hospital of Jilin University from June 2015 to June 2017 were selected.According to different hemostasis methods in operation,they were divided into three groups.The electric coagulation group,96 cases,The suture group,97 cases and the electric coagulation +suture group,96 cases.The general clinical data of age,gravidity and parity history,surgery time and hospitalization time,treatment cost,intraoperative blood loss,postoperative complications,postoperative HPV clearance rate and pregnancy were recorded by reviewing medical records or telephone follow-up.Using SPSS21.0statistical software to analyze all data.Result:(1)The operative time of the three groups(min): The operative time of the suture group(18.65±7.92)was significantly less than that of the electric coagulation group(22.94±6.92)and the electric coagulation+suture group(26.96±8.58).There were significant differences in them(P< 0.001).(2)Intraoperative blood loss in the three groups(ml): Blood loss in the suture group was higher than that in the electric coagulation group and the electric coagulation+suture group,the difference was statistically significant(P<0.0167).There was no difference between the electric coagulation group and the electric coagulation + suture group(P>0.05).(3)The rate of postoperative blood loss in three groups: There were 5 cases,6cases and 5 cases of early postoperative bleeding in the three groups.There was no significant difference in the early postoperative bleeding rates between the three groups(P>0.05).There were 10 cases of postoperative exuvial bleeding in electric coagulation group,which were significantly higher than 2 cases in suture group and 1case in electric coagulation + suture group(P<0.0167).But there was no significant difference in the rate of exuvial bleeding between suture group and electric coagulation + suture group(P>0.05).(4)The rate of HPV clearance in three groups: At 3 months and 6 months after operation,the HPV clearance rate in electric coagulation group and electric coagulation + suture group was significantly higher than that in suture group(P<0.0167).There was no significant difference between electric coagulation group and electric coagulation + suture group(P>0.05).At 9 months and 12 months after operation,the rate of HPV clearance was no significant difference in the three groups(P>0.05).(5)The rate of postoperative infection,cervical tube adhesion,pregnancy,cesarean section,and adverse pregnancy outcomes in the three groups have no obvious difference(P>0.05).In conclusion:1.Electrocautery hemostasis and electrocautery combined with suture hemostasis have the advantages of less intraoperative blood loss and higher HPV clearance rate at3 months and 6 months after surgery.However,the operative time is higher than suture hemostasis,and two hemostasis methods are used at the same time which the operative time is the longest.2.The rate of exuvial bleeding of Suture hemostasis and electrocoagulation combined with suture hemostasis is lower than electrocautery hemostasis.3.The two methods of electrocautery combined with suture hemostasis in cervical cold knife conization can effectively reduce intraoperative blood loss,reduce postoperative exuvial bleeding rate,and increase HPV clearance rate at 3 and 6 months after operation,but no increase the incidence of other complications.Although theoperation time is increased,it can be used as a clinically preferred method.