Analysis Of The Characteristics Of Heart Rate Variability In Female Patients With Acute Myocardial Infarction

Objective: In this study,the characteristics of heart rate variability in female patients with acute myocardial infarction were analyzed through a case-control study,and the evaluation of heart rate variability on short-term prognosis of patients with acute myocardial infarction was discussed.Methods: A total of 152 patients diagnosed with acute myocardial infarction in the department of cardiovascular medicine of Anhui province hospital from July 2016 to July 2017 were enrolled in this study.Females and males were divided into two groups according to gender.The type of myocardial infarction was recorded,and compare two groups of patients with baseline data,left ventricular ejection fraction(LVEF)was measured by Doppler ultrasound,and 24-hour ambulatory electrocardiography was performed.The time and frequency domain indices of mean heart rate(HR)and heart rate variability(HRV)were compared between the two groups.The incidence of major adverse cardiovascular events(MACE)within six months.Results: A total of 152 patients were enrolled in the study,including 52 in the female group and 100 in the male group.Baseline data were compared between the two groups in terms of age,history of hyperlipidemia,systolic blood pressure at admission,diastolic blood pressure,and previous percutaneous coronary stent implantation.History of surgery(PCI),low-density lipoprotein cholesterol(LDL-C),high-density lipoprotein cholesterol(HDL-C),beta blocker use,left ventricular ejection fraction(LVEF),no difference Significance(P>0.05);however,compared with the male group,the female group had a high proportion of hypertension and diabetes(χ2=9.438,P<0.01;χ2=6.859,P<0.01),and the proportion of smoking was low(χ2=26.222,P<0.01),the difference was statistically significant;compared with the male group,the female group had a faster HR [(76.42±11.52)vs(72.56±10.44),P<0.05],time domain index,female group SDNN,SDANN,SDNN Index,r MSSD,and p NN50 were lower than those in the male group(P<0.05).In the frequency domain,the HF,LF,and LF/HF in the female group were lower than those in the male group(P<0.05).The incidence of MACE in the female group was significantly higher than that in the follow-up for half a year.Male group(21.2% vs 8.0%,P<0.05);major adverse cardiovascular events occurred Compared with the group without major adverse cardiovascular events,HR(χ2=9.438,P<0.05)was found to be statistically significant.Among the heart rate variability,the MACE group was less than the MACE group SDNN(χ2=2.092,P<0.05),SDANN(Χ2=2.299,P<0.05),LF(χ2=2.050,P<0.05),LF/HF(χ2=2.126,P<0.05),statistically significant,and SDNN Index(P=0.893),r MSSD(P=0.734),p NN50(P=0.856),HF(P=0.351)were not statistically different.Conclusion: Female patients with acute myocardial infarction have more comorbidities than male patients.In terms of heart rate variability,the average heart rate is fast,the heart rate variability is significantly lower in the time domain and frequency domain,and the short-term prognosis is poor,which suggest that women may have more severe cardiac autonomic dysfunction after acute myocardial infarction.Decreased heart rate variability can be used as an important clue to early identification of major adverse cardiovascular events in patients with acute myocardial infarction.