Effects Of Different Proportion Of Etomidate Combined With Propofol On Painless Gastroscopy In Elderly Patients Were Evaluated

Objective:To investigate the clinical value and safety of etomide and propofol in the examination of painless gastroscopy in elderly patients,and to study a relatively good ratio scheme.Methods:90 elderly patients with painless gastroscopy were examined in our hospital from October 2017 to June 2018.Random group P（simple 1%propofol）,EP1group（0.2%etomide 10MG mixed with 1%propofol 150mg,capacity ratio 1:3）,EP2group（0.2%etomidate 20mg mixed with 1%propofol 200mg,capacity ratio 1:2）,30cases per group.Record the heart rate（HR）,pulse oxygen saturation（SpO₂）,average arterial pressure（MAP）before anaesthesia（T1）,into the esophagus（T2）,and end ofanaesthesia（T3）of the patient and observe the patient’s recovery time,outoventricular time,and adverse reactions.situation.Results:Before anesthesia（T1）and at the end of anesthesia（T3）,there was nosignificant difference among the three groups（P>0.05）,but heart rate（HR）,pulse oxygen saturation（SpO ₂）,mean arterial pressure（MAP）in group P at esophageal intake（T2）were significantly lower than those in group EP1 and EP2（P<0.05）,but there was no significant difference between group EP1 and EP2（P>0.05）.The addition of etomidate did not prolong the recovery time and the time of leaving the room（P>0.05）.The adverse reactions of respiratory depression（hypoxemia）,circulatory depression（hypotension）and injection pain in EP1 group and EP2 group were lower than those in P group（P<0.05）,and the adverse reactions of muscle spasm in EP2group were higher than those in P group and EP1 group（P<0.05）.There was nosignificant difference in nausea and vomiting among the three groups（P>0.05）.Conclusion:The effect of etomidate combined propofol on the circulatory system and respiratory system of patients is small,the incidence of injection pain is low,and the combination of small doses（0.2%etomidate 10 mg and 1%propofol 150 mg mixed,the capacity ratio 1:3）The incidence of muscle fibrillation is lower when applied.It is a safe and effective method of anesthesia and is worth promoting.