Herapeutic Effect Of Catheter-directed Thrombolysis For Acute Lower Limb Deep Venous Thrombosis

Objective:To evaluate the clinical efficacy of catheter-directed thrombolysis(CDT)in the treatment of deep venous thrombosis(DVT)the incidence of post-thrombotic syndrome(PTS).Methods:The clinical data of 80 patients with DVT in lower limb treated in vascular surgery department in our hospital were retrospectively analyzed.The patients were divided into CDT group(40 cases)and Regular anticoagulation group(40 cases),in the same period.Circumference difference between suffered limb and healthy one before and after treatment were compared and calculated.Follow up 24 months for the Villalta score,incidence of PTS and patency in Iliac venous.Results:Preoperative and postoperative thigh /calf circumference difference were significantly regressed,especially in the treatment group.The follow-up showed Villalta score of control group(5.22±0.71)was higher than treatment group(3.26±0.88)and significantly different(P<0.05).The PTS incidence of control group(18/40,45.00%)was higher than that of treatment group(11/40,27.50%),the difference was statically significant(P<0.05).The patency in Iliac venous of treatment group(97.43%)was higher than that of control group(92.10%),the difference was statically significant(P<0.05).Conclusion:CDT combined with regular anticoagulant is safe and effective in the treatment of DVT,and it has the effect of reducing the incidence of PTS.