| Objective: 1.By analyzing the characteristics of the lung function test index of asthmatic children in west Guangxi,we can find out indicators that were sensitive to evaluate the condition.2.By analyzing the distribution of lung function damage in asthmatic children in west Guangxi,the relationship between the change of asthma and the severity of lung function injury 、 lung function index was assessed.3.To explore the characteristics and significance of flow volume ring shape of asthmatic children in west Guangxi.Methods: A total of 192 children who were treated in our hospital from June,2016 to December,2017 were selected.Their family was located in the western Guangxi area.Among them,105 children with asthma were less than 5 years of age and 87 cases of children were aged 5 and above.According to the condition,children can be divided into acute attack period group,chronic duration and clinical remission group.At the same time,70 children from the Guangxi area in our hospital were selected as the control group.Among them,40 patients were under 5 years old and 30 patients were in the group of 5 years old.Using the MS-PAED lung function instrument of German JAGER company,the function test of moisture breathing was performed in the group under 5 years old,and the lung ventilation function was examined in the group above 5 years old.Results: The results of tidal air respiratory function detection(1)Compared with the control group:TPTEF/TE、VPTEF/VE、VT/kg、Ti/TE、TEF25 and TEF50 were all reducedin asthma;(2)Compared with the clinical remission period,TPTEF/TE、VPTEF/VE and TEF25 were all reduced in the acute episode and chronic duration;(3)There was a significant difference in the distribution of damage to acute episodes,chronic duration and clinical remission;(4)Morphological changes of asthmatic moisture flow volume loop(TBFV loop):Asthmatic children TBFV loop of normal lung function closed to ellipse,asthmatic children type ring of abnormal lung function was stout.The more severe the obstruction,the greater the slope of the descending branch of the exhalation phase.Routine ventilation and pulmonary function examination results(1)Compared with the control group:FEV1、FEV1/FVC、PEF、FEF25、FEF50、FEF75、MMEF were reduced;(2)Compared with the clinical remission period: FEV1、FEV1/FVC、PEF、FEF25、FEF50、FEF75 、 MMEF of acute onset and chronic duration were all reduced;(3)There was a significant difference in the distribution of damage to acute episodes,chronic duration and clinical remission;(4)In acute episodes、chronic duration,FEV1、FEV1/FVC were the most abnormal in atmospheric channel parameters,and the small airway parameters are mainly caused by FEF50、FEF75.Most of the atmospheric duct parameters in clinical remission were normal,but the small airway function was still abnormal;(5)In asthmatic children,the Maximum expiratory volume ring(MEFV loop)showed the descending branch is concave to the horizontal axis in exhalation phase.Conclusion: 1.Moisture breathing lung function indexes of asthma children in western Guangxi of TPTEF/TE、VPTEF/VE、VT/kg、Ti/TE、TEF25、TEF50 and Pulmonary ventilation indexes of FEV1、FEV1/FVC、FEF25、FEF50、FEF75、MMEF75/25 were sensitive indexes of reflecting the condition.2.Moisture breath TPTEF/TE、VPTEF/VE、TEF50、TEF75 and pulmonary ventilation FEF25、FEF50、FEF75、MMEF75/25 were important indicators of small airway obstruction.Moisture breath VT/kg、PTEF and pulmonary ventilation FEV1、FVC、FEV1/FVC、PEF were indicators of atmospheric obstruction.The flow volume ring had some significance in thejudgment of airway obstruction.Children with asthmatic children in the western region of Guangxi were large and small respiratory dysfunction but mainly obstructed by small airway obstruction.3.The small respiratory dysfunction of some children in clinical remission period still exists,indicating that the clinical symptom relief does not represent the complete recovery of small airway function,and the children with asthma should adhere to long-term standardized treatment. |
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