| ObjectiveUsing the theory of Jingjin,the early knee osteoarthritis patients were used as the research object,and the influence of Traditional Chinese Medicine Orientation Osmotherapy on the functional activities and gait characteristics of patients with early knee osteoarthritis was analyzed to evaluate the clinical efficacy.Interventional therapy for osteoarthritis seeks a simple,safe,effective,and patient-acceptable treatment.MethodsPatients with early knee osteoarthritis who were admitted to our hospital from July 2017 to December 2018 were randomly divided into observation group and control group,with 36 cases in each group.The control group was treated with conventional celecoxib combined with glucosamine hydrochloride,and the observation group was treated with Traditional Chinese Medicine Orientation Osmotherapy in the basic treatment of the control group.The two groups were treated for 4 weeks respectively.By recording the knee VAS score,knee joint activity,WOMAC score,clinical efficacy and gait observation indicators(including support time,percentage of support time,percentage of foot impulse and step angle)before and after treatment,SPSS was used 20.0 statistical software performed statistical analysis on the collected data.ResultsThe complete follow-up cases of the observation group and the control group were 31 cases and 32 cases respectively.There were no significant differences in gender,affected side,age,body mass index and course of disease between the two groups(P>0.05),which were comparable.1.VAS scores:The scores of the two groups were significantly higher than those of the same group before treatment(P=0.000).The score difference between the two groups was statistically significant(P=0.000),indicating that the analgesic effect of the observation group was more significant.2.WOMAC score:The scores of the two groups were significantly different from those of the same group before treatment(P=0.000).The difference between the two groups was statistically significant(P=0.000),indicating that the improvement of the observation group function was more significant.3.Knee activity:The two groups were compared with the same group before treatment,with a certain degree of change(P=0.000).The difference between the two groups was statistically significant(P=0.011),indicating that the degree of joint mobility was better in the observation group than in the control group.4.Celecoxib taking time:During the treatment period,the time of taking celecoxib in the two groups was compared.The average number of days in the control group was higher than that in the observation group.The difference between the groups was statistically significant(P=0.000),indicating that the observation group can shorten the time of taking Non-steroidal anti-inflammatory drugs by intervening early KOA.5.Clinical efficacy:The clinical efficacy after treatment was statistically significant(P<0.05).The clinical efficacy of the observation group(90.32%)was higher than that of the control group(71.87%).The total effective rate of the two groups was 80.95%.6.Gait indicators:(1)gait support time on the affected side:the two groups were significantly reduced compared with the support time before treatment in the same group(P=0.000).The difference in support time between the two groups was statistically significant(P=0.007),indicating that the observation group improved the support time of the affected side better than the control group.(2)Percentage of time in each stage of affected side support period:After treatment,the control group was compared with the same stage before treatment,the percentage of time did not change significantly,the difference was not statistically significant(P=0.221;P=0.840;P=0.071;P=0.832);the observation group was compared with the same stage before treatment,The percentage of time varies significantly(P=0.000;P=0.000;P=0.000;P=0.002),and the percentage of time in each phase tends to the normal range.The difference of support period between the two groups was statistically significant(P=0.047;P=0.000;P=0.036;P=0.020),indicating that the change of the support period of the observation group was greater than that of the control group.(3)Percentage of foot impulse:After treatment,there was no significant change in the percentage of arch impulse in the two groups(P=0.411 in the control group and P=0.076 in the observation group);the ratio of the heel to the forefoot increased in both groups,and the difference was statistically significant compared with before treatment.(Control group: P=0.017,P=0.029;Observation group:P=0.000,P=0.000),and the corresponding difference was statistically significant(P=0.005,P=0.026),indicating the observation group The changes in the heel and forefoot impulses are more pronounced.(4)Step angle:After treatment,there was no significant change in the step angle of the control group compared with before treatment(P=0.070).The step angle of the observation group changed significantly,which was statistically significant(P=0.000).The difference between the two groups was statistically significant(P=0.002),indicating that the observation group has improved step angle.7.Safety observation:In the observation group,1case had local mild skin allergic reaction,and 2 case in the control group developed gastrointestinal discomfort after taking the drug.The remaining patients had no abnormal reactions such as allergies,skin burns,nausea and dizziness during the treatment and follow-up.ConclusionTraditional Chinese Medicine Orientation Osmotherapy combined with basic treatment can promote pain relief and recovery of joint function in patients with early knee osteoarthritis.It can also improve the muscle strength of hip abductors and correct abnormal gait characteristics of patients,which can be used as an important auxiliary measure for prevention and treatment of early knee osteoarthritis. |
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