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Analysis Of Influencing Factors Of Hospitalized Death In Patients With Acute Myocardial Infarction Complicated With Cardiogenic Shock And Emergency PCI

Posted on:2020-03-26Degree:MasterType:Thesis
Country:ChinaCandidate:L B ShenFull Text:PDF
GTID:2404330596983549Subject:Internal medicine
Abstract/Summary:PDF Full Text Request
Objective The data of emergency Percutaneous coronary intervention(PCI)patients with acute myocardial infarction(AMI)and cardiogenic shock(CS)in Ningxia Medical University General Hospital from January 2009 to December 2018 were analyzed to investigate the hospital mortality and its influencing factors in patients with AMI and CS emergency PCI.Methods Through case search,all patients' case data were collected,and the clinical characteristics,hospitalization outcomes,and hospitalization mortality and influencing factors of AMI patients with CS were analyzed by descriptive methods.Results The hospital mortality rate of 269 patients with AMI and CS who underwent emergency PCI was 43.9%(118 cases).Multivariate logistic regression analysis showed age(OR=1.073,95% CI: 1.041-1.105),admission to blood glucose(OR=1.052,95% CI:1.002-1.105),admission to arterial blood lactate(OR= 1.105,95% CI: 1.020-1.198),admitted creatinine(OR=1.008,95% CI: 1.002-1.013),admission LVEF(OR=0.023,95% CI:0.001-0.618),postoperative TIMI blood flow <3(OR=10.634,95% CI: 4.274-26.459),anterior wall infarction(OR=3.327,95% CI: 1.713-6.460)was an independent risk factor associated with hospitalization death in patients with AMI complicated with CS emergency PCI.Receiver operating characteristic curve(ROC)analysis The regression model has a high ability to identify high-risk patients with death,with an area under ROC of 0.840(95% CI:0.792-0.887).Interquartile analysis showed that for every 8 years of age,the risk of death increased by 7.3%;the average increase in blood glucose per hospital was 3.64 mmol/l,therisk of death increased by 5.2%;the average rate of creatinine admitted to hospital increased by 24.23 ? mol/l,and death The risk increased by 0.8%;the mean arterial blood lactate increased by 2.1mmol/l,the risk of death increased by 13.8%;the average LVEF of admission increased by 5.49%,and the risk of death decreased by 2.3%.Conclusion 1.In this study,the hospitalized mortality rate of patients with AMI combined with CS in emergency PCI was 43.9%.2,the determinants of AMI and CS in emergency PCI patients were mainly due to age and severity of illness at admission.TIMI blood flow <3grade after emergency PCI is also an important factor in increasing the risk of hospitalization death.
Keywords/Search Tags:Acute myocardial infarction, cardiogenic shock, interventional therapy, mortality, risk factors
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