Analysis Of Influencing Factors Of Spontaneous Recanalization Of Infarct-related Artery In Patients With STEMI

Objective : To explore the factors affecting the spontaneous recanalization of infarct-related arteries in patients with STIMI.Methods : Patients with ST-segment elevation myocardial infarction admitted to the Department of Cardiology,Ningxia Medical University General Hospital from January 2017 to December 2017 were treated with emergency coronary angiography.There were 719 patients who met the inclusion criteria,including 184 patients with spontaneous recanalization(SR)in the infarct-related artery and 535 patients with spontaneous recanalization(NSR)in the infarct-related artery.Record the clinical baseline characteristics,such as hypertension,diabetes,smoking,drinking,cardiac function(Killip classification);record of blood routine,blood biochemistry,myocardial injury markers,high-sensitivity CRP and other indicators.On the second day of admission,echocardiography was performed to record EF,left ventricular end-diastolic diameter,left ventricular end-segment diameter,left ventricular end-stomach volume,left ventricular end-stomach volume,presence or absence of ventricular aneurysm,presence or absence of abnormal wall motion of the myocardial wall,etc.data.The results of coronary angiography were recorded.Analyze the factors affecting of SR.Results :1.There were 719 patients with STIMI who met the inclusion criteria,184 patients with spontaneous recanalization(SR)in the infarct-related artery,and 535 patients with spontaneous recanalization(NSR)in the infarct-related artery.The spontaneous recanalization rate was 25.6%.2.There were no significant differences in age,gender,ethnicity,BMI,previous PCI history,diabetes,arrhythmia,cerebrovascular disease,incentives,smoking,drinking between the two groups(P>0.05);(1)The history of hypertension and arrhythmia in the spontaneous recanalization group(SR)were lower than those in the spontaneous recanalization group(NSR)(P<0.05);(2)The cardiac function(Killip classification)in the SR group was better than that in the NSR group(P<0.05);(3)The incidence of infarct-related arteries in the SR group was lower than that in the NSR group(P<0.05).;(4)The white blood cell count,neutrophil relative ratio,and high-sensitivity CRP in the SR group were lower than those in the NSR group(P<0.05);(5)Random blood glucose,uric acid,osmotic pressure,aspartate aminotransferase(AST),alanine aminotransferase(ALT),and lactate dehydrogenase in the SR group were lower than those in the NSR group(P<0.05);(6)The troponin I was lower than that in the NSR group(P<0.05);(7)The EF value in the SR group was higher than that in the NSR group(P<0.05);(8)The proportion of abnormal wall motion in the SR group was lower than that in the NSR group(P<0.05);(9)Logistic regression analysis showed that the relative ratio of neutrophils and high-sensitivity CRP were strongly correlated with spontaneous recanalization(SR)of infarct-related arteries.Conclusion : 1.The spontaneous recanalization rate of infarct-related artery(SR)in patients with STEMI was 25.6%.2.The spontaneous recanalization rate is lower in which of the infarct-related artery is the right coronary artery in the STEMI patients.3.STEMI patients with infarct-related arteries spontaneous recanalization patients with better heart function than non-spontaneous recanalization patients.4.The relative ratio of neutrophils and hypersensitive CRP are predictors of spontaneous recanalization(SR)of infarct-related arteries in STEMI patients.