Correlation Study Of Atmospheric Environmental Factors And The State Of Secretory Otitis Media In Major Regions Of Lanzhou

Aim To assess possible correlations between the atmospheric environmental factors and daily visits of outpatient with secretory otitis media（SOM）during the period 2014–2016 in major rigions of Lanzhou.Methods The levels of AQI、PM2.5、PM10、NO₂、O₃、SO₂、CO、AP、RH、W and T were obtained from local monitor stations.Data of patients with SOM were collected from two Grade A Level hospitals in Lanzhou from January 1,2014 to December 31,2016.Descriptive analysis of data was carried out for the study subjects.Spearman correlation coefficients between atmospheric environmental factors and daily visits of patients with SOM were calculated by SPSS statistical software.Lag effects,relative risks（RR）and exposure-response curves were calculated by generalized additive model（GAM）with R software.Results（1）The incidence of SOM in winter and spring was more than that in summer and autumn,which was consistent with the seasonal variation of meteorological environmental factors of Lanzhou.That was,the meteorological conditions and air quality in winter and spring were poor,while in summer and autumn they were relatively good.（2）The number of male outpatients were 1.05,1.08 and 1.09 times of female outpatients during the period 2014-2016,respectively.And aged 0-10 years old outpatients accounted for 31%of the total SOM outpatients.（3）Exposure-response curve showed that PM2.5,PM10,NO₂ and SO₂ were positively correlated with SOM,T was negatively correlated with SOM.When concentration<1mg/m³,CO was positively correlated with SOM.When concentration>1mg/m³,CO was negatively correlated with SOM.When concentration<30 ug/m³,O₃ was positively correlated with SOM.When concentration>30ug/m³,O₃ was negatively correlated with SOM.（4）The factors we studied could significantly affect the number of SOM outpatients within 2-3 days of single lag effects,and 3-4 days of cumulative lag effects.（5）The influential factors on SOM were as follows:PM2.5、NO₂、SO₂、O₃、CO and T.Conclusions The daily average number of SOM patients in different seasons was different in major region of Lanzhou city,with more in winter、spring and fewer in summer、autumn.Age and sex were the important factors affecting the daily average number of SOM patients.Males were more susceptible to SOM than females and children awere more susceptible to SOM than adults.The change of SOM patients was related to air quality,air pressure and temperature.The worse the air quality,the higher the air pressure,the lower the temperature,the more the average daily number of SOM patients.Meteorological environmental factors affected the visits of SOM,and the lagging effect time of different factors were different.Most of the research factors within 3-4 days had a significant impact on the number of patients of SOM.