Multi-slice Spiral CT Perfusion Imaging Study Of Hemodynamics In The Upper Abdomen Donor Flap

Objective:The 256-slice spiral CT whole liver perfusion examination was performed at the Second Affiliated Hospital of Kunming Medical University,and the results were normal subjects.Perfusion parameters of the upper abdomen donor site,including tissue blood flow(TBF),tissue blood volume(TBV),and time to peak(TTP),were measured by re-perfusion of the subject's previous CT image set.To explore the feasibility of multi-slice spiral CT perfusion imaging technique for determining blood perfusion values in the flap area.To analyze the differences of perfusion parameters in different regions of normal upper abdomen,and to explore the possibility of multi-slice spiral CT perfusion imaging technology to provide quantifiable data before and after flap transplantation,and to lay the foundation for the evaluation of basic flaps for future research.Methods:In the Second Affiliated Hospital of Kunming Medical University,50 patients with 256-slice spiral CT total hepatic perfusion were selected.The results were normal and there was no abnormality in the abdominal wall.A full liver CT perfusion image set of the subject was collected.In the post-processing workstation of the 256-slice spiral CT,the perfusion imaging of the upper abdomen flap was performed again.All the images of the subjects were imported into the EBW post-processing workstation,and the images were post-infused with the Functional Perfusion Software Package.The perfusion parameters of the donor flaps in different areas of the upper abdomen of the subjects were measured,and the upper abdomen chest area was calculated.The perfusion parameters of the flaps in the temporal and dorsal regions were compared statistically,and the perfusion values of the upper abdomen flaps in different regions were statistically compared.Results:Kruskal-Wallis-H test was performed on perfusion parameters(TBF,TBV,TTP)on the right side of the upper abdomen(thoracic region,armpit region,and dorsal region).The results were TBF group,TBV group,TTP group,and the p values of all three groups were less than 0.05,indicating that there was at least one pair of TBF groups,and the TBV group and TTP group were statistically different.The TBF,TBV and TTP values for the different regions were then compared by the Bonferroni method(?=0.05).There was a statistically significant difference in TBF between the right dorsal region of the upper abdomen and the thoracic region,dorsal region,and armpit region(p<0.05).The difference in TBV between the dorsal region and the thoracic region and the dorsal region was statistically significant(p<0.05),and the difference in TTP between the thoracic region and the armpit region,dorsal region and armpit region was statistically significant(p<0.05).Paired rank sum tests were performed using perfusion parameters on the left and right sides of the upper abdominal flap region.The difference in TBF and TBV between the left and right sides of the chest was statistically significant(p<0.05).There was a statistically significant difference in TBF and TTP values between the left and right sides of the armpit region(p<0.05).There were no significant differences in the three perfusion parameters between TBF,TBV and TTP on the left and right sides of the back region.Conclusions:1.Multi-slice spiral CT perfusion imaging techniques can be used to determine blood perfusion values in the flap area.2.Multi-slice spiral CT perfusion parameters(TBF,TBV,TTP)in different regions of the upper abdomen have different degrees of difference,which lays a foundation for the future evaluation of hemodynamics in the flap area by multi-slice spiral CT perfusion imaging.3.Multi-slice spiral CT perfusion parameters based on the flap area in different regions of the upper abdomen can be used to evaluate the hemodynamics of each donor flap.which helps clinicians understand and select the appropriate flap for transplantation.4.There was no difference in perfusion parameters(TBF,TBV,TTP)between the left and right sides of the dorsal region of the upper abdomen,which provided a basis for quantitative evaluation of freely selected autologous flap transplantation.