Clinical Observation On The Treatment Of Chronic Fatigue Syndrome(Type Of Liver Depression And Spleen Deficiency) With Jiawei Jiegan Jian

Objective:It aims to observe the clinical efficacy and safety of Jiawei Jiegan Jian on chronic fatigue syndrome(type of liver depression and spleen deficiency),provide certain thought for the pathogenesis and syndrome differentiation of CFS in traditional Chinese medicine(TCM),investigate the TCM treatment for it,explore the classical prescription and broaden its application range,so as to lay a good foundation for in-depth study of CFS.Method:In this subject,72 CFS patients who met the inclusion criteria were screened as the subjects,and were divided into the treatment group and the control group by random number table,36 cases / group,and the patients were single blinded.Chinese medicine Jiawei Jiegan Jian Granules were administrated in the treatment group,and the Chinese patent medicine Shugan Granules were administrated in the control group.How to take:take 1 sachet at a time,dissolve in 150 ml of warm water,and take it orally after breakfast and after dinner.Take 4 weeks as a course of treatment.Observe fatigue scale-14 scores,health survey table scores and TCM symptoms scores before and after treatment to determine the clinical efficacy.Results:1.Pre-treatment comparison between the 2 groups: there was no statistically significant difference in the general data and each scale before treatment between the 2 groups(p>0.05),and the comparative basis was available.2.Pre-and post-treatment comparison within the group: the post-treatment fatigue scale-14 scores of both 2 groups were better than those of pre-treatment(p <0.05),with the difference statistically significant.After treatment,the health survey summary table scores of both 2 groups were better than those before treatment in the following 7 aspects of "emotional function","social function","somatic pain","energy","mental health","general health status" and "health change",p <0.05,with the difference statistically significant.3.Pre-treatment comparison between groups: After treatment,the fatigue scale-14 scores of the 2 groups were compared,and the difference between "body fatigue" and "total fatigue" was statistically significant(p <0.05),the treatment group were better than those of the control group;and the difference in "brain fatigue" between the 2 groups was not statistically significant(p> 0.05).After treatment,the health survey stable scores of the 2groups were significantly different(p < 0.05)in the 6 aspects of "emotional function","social function","body pain","energy","mental health",and "general health status",the treatment group was better than those of the control group;the difference between the 2groups in "physiological function","physiological function" and "health change" was not statistically significant(p> 0.05).After treatment,the TCM symptom scores of the 2groups were significantly different(p < 0.05)in the 5 aspects of "fatigue or emotional discomfort",“discomfort of the whole body”,"inattentiveness or memory loss","eating less and stupidity","shortness of breath",the treatment group was better than those of the control group;there was no statistically significant difference between the 2 groups in the 4aspects of "sighing","restless sleep","epigastric distension" and "abdominal distension "(p> 0.05).Conclusion:Jiawei Jiegan Jian has a certain clinical efficacy on chronic fatigue syndrome of liver depression and spleen deficiency type,which can obviously relieve the symptoms of fatigue,decreased concentration and reduced diet,and has no obvious adverse reactions.