| Objective To observe the clinical efficacy and safety of "Tong Du Tiao Shen" acupuncture method on chronic insomnia,to provide a more effective treatment plan,and to explore the possible mechanism of acupuncture in treating insomnia.based on the HPA axis.Methods Sixty patients with Chronic insomnia were divided into the test group and the control group according to random number table,30 cases in each group.Both groups received unified online sleep health education.The treatment group adopted the method of "Tong Du Tiao Shen"acupuncture method,which selected Baihui(GV20),Yintang(GV29),bilateral Shenmen(HT7)and SanYinjiao(SP6).The control group was treated with sham acupuncture,which was non-meridional and non-acupoint superficial acupuncture.Both groups were treated once every other day,3 times a week for 4 consecutive weeks,a total of 12 times.By comparing the PSQI factor scores and total scores of the two groups of patients and the HAMA,HAMD and FS-14 scale scores,the clinical efficacy of"Tong Du Tiao Shen "acupuncture method was evaluated.Serum cortisol content before and after treatment was detected in two groups of patients to explore the possible mechanism of acupuncture in the treatment of chronic insomnia.Results 1.After treatment,the PSQI factor scores and total scores,HAMA,HAMD,FS-14 scale scores and cortisol levels in the two groups decreased significantly compared with those before treatment(P<0.01).In the control group,PSQI scores of all factors except sleep efficiency were lower than before,with statistically significant differences(P<0.05).Total PSQI scores,HAMA,HAMD and fs-14 scores,physical fatigue scores and serum cortisol levels were lower,with statistically significant differences(P<0.05).2.In the test group,factors and total score of PSQI were improved,and scores of HAMA,HAMD,FS-14 scale and cortisol level were significantly lower than the control group(P<0.01).3.Comparison at the time of follow-up:all scale scores in the experimental group were significantly lower at the time of follow-up than before treatment(P<0.01);Compared to post-treatment:the differences were not statistically significant(P>0.05).The scores of each scale were compared during follow-up:the test group was better than the control group,with significant differences(P<0.01).4.In the test group,the total effective rate was 68.97%(20/29),while 1 case was cured,9 cases strikingly showed effect,10 cases were effective,9 cases were resultless.While 0 cases were cured in the control group,only 1 case strikingly showed effect,5 cases were effective,and 21 cases were resultless.The total effective rate of the control group was 22.22%(6/27),with significant difference(P<0.01).5.Safety evaluation:during the treatment,2 cases of mild adverse reactions occurred in the test group,and 1 case of mild adverse reactions occurred in the control group.Conclusion 1.The method of "Tong Du Tiao Shen" acupuncture method can significantly improve the sleep quality,sleep time,sleep time,sleep efficiency,sleep disturbance,daytime dysfunction and mental state,daytime fatigue state of patients with chronic insomnia Sham acupuncture can also improve sleep,relieve anxiety,depression and physical fatigue,while,The result of " Tong Du Tiao Shen " acupuncture group is significantly better than those of sham acupuncture,and the long-term curative effect was stable at 1 month follow-up after treatment.2."Tong Du Tiao Shen" acupuncture method can reduce the level of blood cortisol,so it is speculated that "Tong Du Tiao Shen" acupuncture method can improve sleep quality by reducing the level of cortisol,the classic indicator of chronic stress,reducing HPA axis activity and reducing arousal.3.The safety of the "Tong Du Tiao Shen"acupuncture method is better. |
PDF Full Text Request