The Value Of Gadoxate Disodium Enhanced Magnetic Resonance Combined With Diffusion Weighted Imaging In The Diagnosis Of Liver Nodular Lesions

Objective:To explore and analyze the value of gadoxetate disodium(Gd-EOB-DTPA)enhanced magnetic resonance imaging combined with diffusion weighted imaging(DWI)in the diagnosis of liver nodular lesions.Materials and methods:This study is a retrospective study and approved by the Research Ethics Committee of Jingzhou Central Hospital(Second Clinical Hospital of Yangtze University),Hubei Province,China.71 patients with clinically diagnosed liver nodular lesions(diameter ?3 cm)and definite lesions were screened from May 2017 to November 2019.1.The diagnostic accordance rates of benign and malignant nodules in the two groups(Gd-EOB-DTPA enhanced MRI+DWI group and general-enhanced MRI+DWI group)were compared.2.The accuracy of qualitative diagnosis of all lesions in Gd-EOB-DTPA enhanced MRI+DWI group and general-enhanced MRI+DWI group was calculated.Results:1.The diagnose accordance rates of the 2 groups of examination methods for various liver nodular lesions(diameter?3cm)are 97.7%and 98.9%.The diagnose accordance rates of general enhanced MRI+DWI group and Gd-EOB-DTPA enhanced MRI+DWI group is higher.Under different liver function conditions(normal group,Child-Pugh A,B and C group),the diagnose accordance rates of Gd-EOB-DTPA enhanced MRI+DWI group was 87.5%,93.9%,87.5%and 78.5%,and the number of general enhanced MRI+DWI group was 87.5%?87.9%?68.8%?78.6%.2.The diagnostic accuracy of the Gd-EOB-DTPA enhanced MRI+DWI group for hepatocellular carcinoma,liver localized dysplasia,liver cirrhosis nodules,liver metastases and hemangiomas were 92%,83.3%,75%,90%,93.8%;and the number of general-enhanced MRI+DWI group were 68%,33.3%,25%,40%,62.5%.The Gd-EOB-DTPA enhanced MRI+DWI group had higher diagnostic accuracy for hepatocellular carcinoma than the general-enhanced MRI+DWI group.3.The diagnostic sensitivity of Gd-EOB-DTPA enhanced MRI+DWI group(80%)was higher than that of general-enhanced MRI+DWI group(55.6%),but the diagnostic specificity of the two was the same.Conclusion:1.Gd-EOB-DTPA enhanced MRI combined with DWI can diagnose common liver nodules(diameter?3cm),such as hepatocellular carcinoma,liver localized dysplasia,cirrhotic nodules,liver metastases and hemangiomas,and the diagnose accordance rates and diagnostic accuracy are highly consistent with the"golden standard"(pathological results).2.The diagnostic accuracy of Gd-EOB-DTPA enhanced MRI combined with DWI for HCC(diameter?3cm)is significantly higher than that of general-enhanced MRI.So for patients with clinically suspected HCC(diameter?3cm),it is recommended to perform Gd-EOB-DTPA enhancement MRI combined with DWI to provide more effective information for the location,quantitative and qualitative diagnosis of the lesions at one time.3.In this study,Gd-EOB-DTPA-enhanced MRI combined with DWI,general-enhanced MRI combined with DWI were used to diagnose hepatic nodular lesions with a diameter of?3 cm.Various typical and atypical imaging signs were summarized and summarized for learning.