Study On(Comparison On The Correlation Between Different Anthropometric Indexes In Relation To Hypertension In Adults)

ObjectivesTo compare the correlation between different anthropometric indexes(BMI,WC,WHR,WHt R,RFM,LAP and BAI)in relation to hypertension in adults,and to distinguish the difference in the efficacy of identifying hypertension.In order to provide supporting data for health institutions on formulating effective prevention and strategies of obesity and hypertension in adult community residents.MethodsIn this study,a multi-stage stratified random sampling method was used to recruit 2034 residents of communities in southern China,aged 18-88 years.General demographic data were collected and the subjects’ height,weight,waist circumference,hip circumference and Biochemical indexes were measured.Pearson correlation analysis was used to analyze the correlation between various anthropometric indicators and their associations with blood pressure,and the relationship between different anthropometric indicators and hypertension was analyzed by binary Logistic regression model.Odds Ratio(OR)and 95% Confidence Interval(CI)were used to reflect the strength of correlation.A restricted cubic spline regression model was used to analyze the dose-response relationship between anthropometric indexes and hypertension.Receiver Operating Characteristic(ROC)and Area Under Curve(AUC)were used to evaluate the ability of different anthropometric indicators to identify hypertension and to calculate the optimal cutoff value.Results1.The prevalence of hypertension in males and females was 27.36% and 18.05%,respectively.In both men and women,anthropometric index values increased with age,and the levels of SBP(Systolic Blood Pressure)and DBP(Diastolic Blood Pressure)increased with the quartets of anthropometric index(BMI,WC,WHt R,WHR,RFM,LAP,and BAI)(P trend <0.001).2.The standardized value of each anthropometric index increased by one standard deviation,the corresponding OR(95% CI)of RFM were 3.03(2.26,4.06)and 2.18(1.50,3.18)for young and middle-aged male,respectively;the corresponding OR(95% CI)of RFM were 1.81(1.30,2.53)and 2.93(1.85,4.65)for young and middle-aged women,respectively.Under the age and gender stratification,the corresponding value were larger than the values of other anthropometric indexes.3.After controlling for confounding factors,with the increase of values of BMI,WC,WHt R and RFM,the strength of correlation with hypertension presented a linear dose-response relationship among men in the restricted cubic spline model(nonlinearity test,c2: 5.24、3.63、3.26 and 6.42,respectively;all P>0.05),while with the increase of values of WHR,LAP and BAI,the strength of correlation presented a nonlinear dose-response relationship(nonlinearity test,c2: 7.87,28.58 and 10.99,respectively;all P<0.05).In women,with the increase of values of WC,WHt R,WHR,RFM and BAI,the strength of association with hypertension presented a linear dose-response relationship(nonlinearity test,c2: 0.29、1.06、1.81、1.26 and 1.81,respectively;all P>0.05),while for BMI and LAP,the strength of association with hypertension presented a nonlinear dose-response relationship(nonlinearity test,c2: 10.70 and 17.12,respectively;both P<0.05).4.The AUC of RFM and WHt R in the differentiation of hypertension in men was 0.750,and the comparison results showed that the AUC value was larger than the corresponding values of BMI(AUC=0.707),WC(AUC=0.734),WHR(AUC=0.687),LAP(AUC=0.687)and BAI(AUC=0.702)(P<0.05).The AUC value of RFM and WHt R in identifying hypertension in women was 0.738,and the comparison results showed that the AUC value was larger than the corresponding value of BMI(AUC=0.699),WHR(AUC=0.682)and BAI(AUC=0.684)(P<0.05).There was no difference in the AUC value of RFM and WHt R in identifying hypertension in both men and women.5.The optimal cutoff value of anthropometric indicators to identify hypertension among men was BMI: 23.00kg/m2;WC: 85.05 cm;WHt R: 0.51;WHR: 0.91;RFM: 24.60;LAP: 45.66 cm.mmol/L;BAI: 25.56,respectively.The optimal cutoff value of anthropometric indicators to identify hypertension among women was BMI: 21.77 kg/m2;WC: 79.90 cm;WHt R: 0.50;WHR: 0.86;RFM: 36.26;LAP: 27.37 cm.mmol/L;BAI: 28.66,respectively.Conclusions1.Different anthropometric indexes were positively correlated with the risk of hypertension in both men and women,and their continuous changes showed a significant dose-response relationship with hypertension.2.Compared with other anthropometric indexes,the new anthropometric indexes RFM are more strongly correlated with hypertension in adults.RFM is comparable to WHt R in identifying hypertension in adults,and superior to other anthropometric indexes(such as BMI,WC,WHR,LAP,and BAI).It suggests that it is necessary to control RFM in the normal range in order to achieve a better effect of monitoring and preventing hypertension among adults.3.The optimal cutoff values for anthropometric indexes to distinguish hypertension in men and women were: BMI: 23.00kg/m2 and 21.77 kg/m2;WC: 85.05 cm and 79.90cm;WHt R: 0.51 and 0.50;WHR: 0.91 and 0.86;RFM: 24.60 and 36.26;LAP: 45.66 cm.mmol/L and 27.37 cm.mmol/L;BAI: 25.56 and 28.66,which can provide a reference for guiding the population to make reasonable use of anthropometric indicators to evaluate the degree of obesity,and to intervene obesity in advance,so as to realize the early prevention and control of hypertension.