| [Objective]This study aimed to summarize the hospitalization data of 189 patients with bronchiectasis retrospectively,based on analyzing their clinical features,exploring the value of different severity assessment scales for their severity assessment,so as to refine the clinical understanding of the disease.[Methods]The clinical data were collected including age,duration,gender,clinical manifestations and signs,from 189 patients with bronchiectasis who were admitted to the Department of Respiratory Medicine,Zhangjiagang Hospital of Traditional Chinese Medicine,from January 1,2015 to December 30,2018,and confirmed by HRCT.Etiology,laboratory,imaging,bronchoscopy results,etc.,using the FACED rating scale,BSI rating scale and modified simplified BSI rating scale to assess their severity.[Results]1.Among the 189 patients with bronchiectasis,82 were male and 107 were female,with an average age of 61.9±14.9 years,with an average duration of 20.7±8.6 years;142 patients had no clear cause,accounting for 75.1%,and 47 patients with clear etiology had previous infections.The main causes were 29 cases,accounting for 15.3%,of which tuberculosis infection was the primary factor;compared with patients with saccular type and main column expansion,sac-type patients are more common with wet rales.(P<0.05).2.Of the 107 patients who underwent bronchoscopy,44 of them had bronchial mucosal congestion and edema(44/107,41.12%),and 38 of them saw massive sputum accumulation in the airway(38/107,35.51%).3.A total of 129 patients were examined by sputum culture.Among them,87(87/129,67.44%)detected pathogens,82 patients were bacteria(82/129,63.56%),and 13 patients were positive for fungal culture(11 of them)Combined with bacterial infection),47 of the 82 sputum culture-positive patients were Pseudomonas aeruginosa(57.32%),11 were Acinetobacter baumannii(13.41%),and 9 were Staphylococcus aureus(10.98%).4.HRCT showed that more than 2 lobes were involved in mostly patients with bronchiectasis(147/189,77.8%),mainly left lower lobe involved(140/189,74.1%);49 cases(25.93%)with cylindrical-dominated type,mainly in cystic 22 cases(11.64%);62 cases(32.80%)with varicose veins-dominated type;and 56 cases(29.63%)with passive traction-dominated type.5.Pulmonary function tests showed that 60 patients had obstructive ventilatory dysfunction(60/106,56.60%),and the percentage of lung function indicators of various types of branch expansion accounted for the normal expected value,there was no significant difference between the groups.6.There were no significant differences in the ratios of FACED scores,BSI scores and modified simplified BSI scores for patients with different severity(P>0.05),and there were also no significant difference between the two groups(P>0.05).[Conclusions]1.Bronchiectasis is more common in middle-aged older women.About 3/4 of the patients with enlarged etiology are unknown,and previous infections(especially tuberculosis infection)are the main cause.2.The patients with saccular-dominated bronchiectasis were more common than those with cylindrical-dominated type in wet rales.Sputum culture revealed that more than half of the bronchiectasis patients were detected Pseudomonas aeruginosa.3.A modified simplified simplification severity index(modified simplified BSI)scale consisting of age,mMRC score,number of acute exacerbations in the most recent year,CRP,PCT,and eosinophil ratio can be used as an approximation of the severity of branch expansion,has a certain clinical value. |
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