Effect Of Lactase Deficiency On Weight、serum Albumin Concentration And High-density Lipoproteins Concentration In Preterm

Objective:To investigate the effects of lactase on weight gain,serum albumin concentration and high-density lipoprotein concentration in premature infants.Methods:80 premature infants(33w≤GA ≤34w)with birth weight(WT)of 1670g≤WT≤3013g were hospitalized in Neonatal intensive care unit(NICU)of binzhou medical college affiliated hospital on January 1,2017 to January 1,2018.All the premature infants were fed with formula milk on the day after birth or the second day,and the enteral feeding fluid amount at 1 week after birth was above 50%of daily fluid intake.The fecal reducing sugar test and urine galactose test were used as the diagnostic criteria to determine whether the premature infants were lactase deficient after feeding formula milk for 1 week and postmenstrual age for 37 weeks.40 premature infants with positive urine galactose and fecal reducing sugar were selected as lactase deficient group when formula milk was fed for 1 week and postmenstrual age 37 weeks.The control group included 40 premature infants whose urine galactose and fecal reducing sugar were negative after feeding formula for 1 week.The body weight,serum albumin concentration and high-density lipoprotein concentration of the premature infants in each group were measured at 1 and 2 weeks of formula feeding and postmenstrual age 37 weeks.Then statistical analysis was performed to observe whether the nutritional indexes of the two groups of premature infants had statistical significance.Results:Compared with the control group,the lactase deficiency group was fed formula milk for 1 week,and there was no statistical significance in weight growth,serum albumin concentration and high-density lipoprotein concentration between the two groups(P>0.05).Infant formula feeding for 2 weeks,weight gain,the difference data between the two groups was statistically significant(P<0.05),serum albumin concentration,high-density lipoprotein concentration was’t statistically significant(P>0.05).Postmenstrual age 37 weeks,there were statistically significant differences in weight gain,serum albumin concentration and high-density lipoprotein concentration between the two groups(P<0.05).Conclusion:Lactase deficiency of the premature infant weight gain,serum albumin concentration,lipoprotein concentration has a certain impact.Lactase can promote the weight growth of premature infants.The concentration of serum albumin and lipoprotein increased.