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Screening Of Early Warning Parameters Of Dengue Fever Syndrome In Mengla County Based On Space-Time Rearrangement Scanning Statistics

Posted on:2021-04-21Degree:MasterType:Thesis
Country:ChinaCandidate:R Y GuFull Text:PDF
GTID:2404330605481139Subject:Epidemiology and Health Statistics
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Objective:1.To do epidemiological analysis of dengue fever cases in Mengla County in 2017.2.To establish the combination of time and space parameters for spatiotemporal rearrangement scanning.3.The spatial and temporal rearrangement of dengue cluster events was performed by means of dengue syndrome to evaluate the effects of different spatiotemporal parameter combinations on the early warning effect.4.To select the best spatiotemporal parameter combination for early warning of dengue syndrome and establish a perfect early warning model of dengue syndrome based on spatiotemporal rearrangement scan statistics.Methods:The data of dengue syndrome in eighty medical institutions(including township hospitals and village clinics)in the sympom monitoring system of medical institutions in Mengla County in 2017 and the data of reported cases of dengue in the direct reporting system of infectious diseases were collected;Using Excel to describe the time,region and population distribution of dengue fever;The Java server page is scanned to establish different spatiotemporal parameter combinations(X,Y).X was the time parameter and Y was the space parameter,the maximum number of early warning days was set as four days,including the date of the gathering event,a total of five days;The dengue fever clusters in mengla county in 2017 were scanned day by day in time and space,and the sensitivity and the number of days of advance warning were used as the warning indicators to comprehensively evaluate the warning effects of nine warning schemes.Results:1.A total of two hundred and forty-seven cases of dengue fever were reported in Mengla County in 2017,with an incidence rate of 85.79/100.000.The peak of incidence is mainly from August to November;cases of dengue fever reported by the infectious disease direct reporting system were distributed in eight medical institutions.Mengla County people's hospital has the largest number of reported cases;the ratio of male to female was roughly balanced(about 1:1).The largest population distribution was 100 cases of farmers(40.49%),followed by 50 cases of business service personnel(20.24%).2.Nine different spatiotemporal parameter combinations were used to scan a total of 225 times which were performed for five dengue fever clusters in Mengla County in 2017.The aggregation region,LLR,RR and P values of the warning under each scan combination were obtained.3.Sensitivity analysis of nine parameter combinations for five dengue aggregation events:(3,10),(4,10),(5,10),(4,15),(5,15)combination alerted to five dengue aggregation events,the sensitivity was 100%;(3,15)combination alerted to four dengue aggregation events,the sensitivity was 80%;(3,5),(4,5),(5,5)combination alerted to three dengue aggregation events Event,sensitivity was 60%.4.Analysis of the early warning time of five dengue aggregation events by nine parameter combinations:(3,10)combination early warning time of five dengue aggregation events were three days,four days,four days,one day and one day respectively,with an average early warning time of two point six days;(4,10),(5,10)combination early warning time of five dengue aggregation events were two days,three days,four days,one days and zero day respectively,with an average early warning time of two days;(3,15)combination early warning time of five dengue aggregation events were zero day,four days,four days,one day and one day respectively,with an average early warning time of two days;(5,15)combination early warning time of five dengue aggregation events were one day,four days,four days,one day and zero day respectively,with an average early warning time of 2 days;(4,5),(5,5),(4,15)combination early warning time of five dengue aggregation events were zero day,four days,three days,one day and zero day respectively,with an average early warning time of one point six days:(3.5)combination early warning time of five dengue aggregation events were one day,four days,three days,zero day and zero day respectively,with an average early warning time of one point six days.5.Analysis of the duration warning time of five dengue aggregation events by nine parameter combinations:(3,10)combination among the five dengue aggregation events,the average duration warning days were two point two days;(4,10),(5.10).(5.15)combination among the five dengue aggregation events.the average duration warning days are two days;the average duration warning days of other Parameter combinations are less than two days.Conclusions:1.Dengue fever has an obvious seasonal trend in Mengla County,and the cases are mainly concentrated in summer and autumn.In this period of time,we should strengthen the corresponding prevention and control of dengue fever,especially the main gathering areas of farmers and commercial service groups.2.Based on the data of dengue syndrome,the time-space rearrangement scanning of dengue clustering events in Mengla County is carried out,and the optimal time-space clustering combination is selected.In the future,the combination of(3,10)parameters can be used preferentially in the early warning of dengue outbreak in this area by using dengue syndrome;In addition,the combination of(4,10),(5,10),(5,15)parameters can be used as an alternative parameter combination.3.In the future,when optimal parameter combination is used for dengue fever early warning,graded response can be adopted according to the actual situation.Maximally ensures that real aggregation events are detected while avoiding excessive waste of resources.
Keywords/Search Tags:dengue fever, space-time rearrangement scan, space-time aggregation, parameter filtering, symptom monitoring
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