Effect Of Growing Development And Electroencephalogram In The Rat After Prenatal Exposure To 1800 MHz And WiFi Electromagnetic Fields

Objective:To explore the effects of Growing Development and Electroencephalogra-m(EEG)in the Rat after Prenatal Exposure to 1800 MHz and WiFi Radio Frequency Electromagnetic Fields.Method:There were 36 healthy 7 weeks old SPF Wistar rats,including 24 females and 12 males.After two weeks for environmental adaptation and successful mating,the pregnant rats were randomly divided into three experimental groups and three control groups(4 rats in each).The experimental groups included 1800 MHz exposure grou,1800 MHz+WiFi exposure group,WiFi exposure group.Simultaneously,the virtual exposures were set as controls for the there experimental groups.The power density is 1.0 mw/cm2.The exposure time was from 0 pregnant day to 20 pregnant days,every night 20:00 to 8:00 in the morning the next day.Rats in each group were all free to drink and eat during exposure,and the environmental background conditions including temperature,humidity were stable.After the completion of exposure,the indicators of growing development were observed and measured in offspring rats.After 21 days,weaning training.When the offspring were ten weeks old,12 rats in each group were randomly sampled for Electroencephalography and blood was immediately taken from the aorta abdominalis.Microelement of zinc,copper,iron and manganese in serum were measured by inductively coupled plasma mass spectrometry.Results:1.Physiological development indicators:There were statistically significant di-fferences in body weight between the exposure group and the control group,the exp-osure group was smaller than the control group.The body weight and the open eye time of the 1800 MHz+WiFi exposure group and the WiFi exposure group was dif-ferent from that of the control group(p<0.05),and the body weight of the 1800 MHz+WiFi exposure group was smaller than that of the WiFi exposure group,but the open eye time was longer than that of WiFi exposure group.There was no statistical difference in other physiological development indexes.2.EEG experiment:(1)Total power:The total EEG power of the 1800 MHz+WiFi exposure group was different from that of the control group and the WiFi exposure group(p<0.05),The total EEG power of the 1800 MHz+WiFi exposure group was higher than that of the control group and the WiFi exposure group.(2)Average power of 6 bands:The average power of frequency band ?l,frequency band ? and frequency band ? in the 1800 MHz+WiFi exposure group was different from that of the control group(p<0.05),and higher than that in the control group.The ? band average power of the 1800 MHz+WiFi exposure group was higher than that of the 1800 MHz exposure group,and the ? band average power was higher than that of the WiFi exposure group.There was no statistical difference in other bands.(3)Absolute power on C3 side of 6 bands:The absolute power of ? band and ?band in the 1800 MHz+WiFi exposure group was different from that of the control group(p<0.05),and higher than that in the control group.The absolute power of ?band in the 1800 MHz+WiFi exposure group was higher than that in the 1800 MHz exposure group,and the ?2 band and ? band was higher than that in the WiFi exposure group.There was no statistical difference in other bands.(4)Absolute power on C4 side of 6 bands:There were statistically significant differences in ? bands between the 1800 MHz+WiFi exposure group and the control group(P<0.05).The absolute power of ? band in the 1800 MHz+WiFi exposure group was higher than that in the control group.3.Trace Elements in serum:The Zinc element in the 1800 MHz+WiFi exposure group was lower than that in the control group.The element of copper and iron in the 1800 MHz+WiFi exposure group was higher than that in the control group(p<0.05).The copper element in the 1800 MHz+WiFi exposure group was higher than that in the 1800 MHz exposure group(p<0.05).There were statistically significant differences in Manganese element between the exposure group and the control group,the exposure group was higher than the control group(p<0.05).Conclusion:Under the experimental conditions:1.There was a falling trend on body weight of offspring rats exposed to 1800 MHz,WiFi and 1800 MHz+WiFi radio-frequency fields.There was a lengthen trend on eyes opening time of offspring rats exposed to 1800 MHz and WiFi radio-frequen cy fields.2.There was a increased trend on the total power,fast wave band(? band)and slow wave band(? band and ? band)in hippocampal EEG of offspring rats exposed to 1800 MHz and WiFi radio-frequency fields.3.There was a falling trend on trace element of Zinc,and the increased tre nd on trace element of copper and iron in serum of offspring rats exposed to 1800 MHz and WiFi radio-frequency fields.There was a increased trend on Ma nganese element of offspring rats exposed to 1800 MHz,WiFi and 1800 MH z+WiFi radio-frequency fields.