Effects Of Installation Of Pacemaker In Different Parts On Cardiac Function And Quality Of Life In Patients With Sick Sinus Syndrome

Objective: To observe the cardiac function indexes,plasma brain natriuretic peptide(BNP)levels of patients with pathological sinus node syndrome(HBP),right ventricular apex pacing(RVAP)and right ventricular septal pacing(RVSP)Effects of 6-minute walking test(6-MWT)results,incidence of AF,and quality of life score.Methods: A retrospective analysis was used to select 108 patients who were diagnosed with sick sinus syndrome and installed pacemaker in Weifang Yidu Central Hospital?Jinan central hospital and Yantai Yuhuangding hospital from August 2015 to May 2018.There were 32 successful patients(HBP group),38 patients with right ventricular apical pacing implantation(RVAP group),and 38 patients with right ventricular septal pacing implantation(RVSP group).The 6-minute walk test(6-MWT),cardiac ultrasound,and B-type natriuretic peptide(BNP)were used to evaluate the cardiac function of patients,and the SF-36 quality of life questionnaire was used as a means of evaluating quality of life.6-MWT results before,6 months after surgery,left ventricular end-diastolic diameter(LVEDD),left atrial end-diastolic diameter(LAEDD),left atrial volume index(LAVI),and left ventricular ejection fraction(LVEF),The incidence of atrial fibrillation(atrial fibrillation),the plasma BNP value,and the score of the SF-36 quality of life questionnaire evaluated changes in cardiac function and quality of life in the three groups of patients.Results:1.The results of general data analysis showed that the three groups of patients were not statistically significant in terms of age,gender,comorbidities,smoking status,and whether atrial fibrillation(P> 0.05),and they were comparable.2.The comparison of the cardiac function indexes of the three groups of patients before and6 months after operation showed that there was no statistical difference in the cardiac function indexes of the three groups of patients before surgery(P> 0.05).After 6 months,LAEDD in the three groups were all higher than before,but there was no statistical difference between the three groups(P> 0.05).Among them,LVEDD,LAVI,and LVEF were higher in the HBP group after 6 months In the RVAP group and the RVSP group,the difference was statistically significant(P <0.05).3.The 6-MWT results of the three groups of patients before and 6 months after operation showed that there was no statistical difference in the 6-MWT results of the three groups of patients before surgery(P> 0.05).The 6-MWT results in the HBP group at 6 months after operation were higher than those in the RVAP and RVSP groups,and the difference was statistically significant(P <0.05).4.The plasma BNP levels of the three groups of patients before and 6 months after operation showed that there was no statistical difference in the plasma BNP levels of the three groups of patients before surgery(P> 0.05).The BNP values of HBP group at 6months after operation were lower than those of RVAP group and RVSP group,and the difference was statistically significant(P <0.05).5.The incidence of AF in the three groups of patients before and 6 months after operation showed that there was no statistical difference in the incidence of AF in the three groups before surgery(P> 0.05).The incidence of atrial fibrillation in the HBP group was significantly lower than that in the RVAP and RVSP groups at 6 months after operation,and the difference was statistically significant(P <0.017).6.The quality of life scores of the three groups of patients before and 6 months after surgery showed that the quality of life of the three groups of patients was scored from five aspects,including social function,physical pain,mental health,physiological function,and emotional function.There was no statistically significant difference in the quality of life scores of the group patients(P> 0.05).The quality of life scores of the three groups of patients at 6 months after surgery were improved compared with those before surgery.The improvement of the quality of life scores of the HBP group at 6months after surgery was significantly better than that of the RVAP and RVSP groups(P<0.05).Conclusions:1.Compared with the right ventricular apex pacing and right ventricular septum pacing methods,Heath pacing is more effective in treating patients with sick sinus syndrome.2.Heath pacing can significantly improve the patient's cardiac function index,reduce the incidence of atrial fibrillation,and increase the patient's multiple quality of life scores,thereby improving patient prognosis.