| Objective: To analysis the incidence of new atrial fibrillation after pacemaker implantation,find the relevant risk factors as well as study whether pacemakers with anti-atrial fibrillation function can play a role in preventing atrial fibrillation after opening these functions.Methods: Participants are 125 patients without documented atrial fibrillation and incomplete information who implantatde pacemaker during 2010 to 2018 in our hospital.All patients conform to inclusion criteria and don’t meet exclusion criteria.Each patient should accept follow-up on 1 month,3 month,6 month and 1 year at the cardiovascular clinic to adjust pacemaker and do a 12-lead electrocardiogram.If the patient feel sick,he or she is told to have a 12-lead electrocardiogram immediately and then have a programme-controlled with all these data.Results: According to the follow-up analysis of the above 125 patients,a total of 22 patients,accounting for 17.6% of the total number of patients in the group,have atrial fibrillation or automatic mode conversion meeting the occurrence standard of atrial fibrillation within one year after pacemaker implantation.In the study of the basic conditions and previous diseases of new onset atrial fibrillation patients,14 patients(64%,P=0.021)were complicated with hypertension,14 patients(64%,P=0.004)were complicated with diabetes,12 patients(55%,P=0.007)were diagnosed with atrial premature or short burst atrial tachycardia by preoperative dynamic electrocardiogram,13 patients(59%,P=0.035)were diagnosed with previous drinking history,and 11patients(50%)were overweight or obese.P=0.017),suggesting that atrial fibrillation is high in patients complicated with hypertension,diabetes,atrial premature or short atrial tachycardia,drinking history,overweight or obesity.After analyzing the admission test data of these patients,it was found that blood uric acid(UA:360.59±78.65umol/l,P=0.005),plasma B-type natriuretic peptide(BNP:322.18±190.137 pg/ml,P=0.002),left atrial diameter(LA:41.73±5.75 mm,P=0.001),ejection fraction(EF:56.05±4.72%,P=0.000)of these patients with atrial fibrillation,suggesting that UA,BNP,LA,EF are related to new atrial fibrillation in patients after pacemaker operation.In the analysis of pacemakers and their functions,twenty-one pacemakers in the atrial fibrillation group have anti-atrial fibrillation function(95%,P=0.000),suggesting that such functions have an impact on new atrial fibrillation.In the analysis of pacemaker and its special functions,14 patients(14%)with MVP function,3 patients(3%)with Search AV function and 46 patients(45%)with VIP function in non-atrial fibrillation group,P=0.022,suggesting that activation of relevant functions can prevent atrial fibrillation after pacemaker operation.Finally,logistic regression analysis was carried out for the above factors affecting new atrial fibrillation.It was found that overweight or obesity,large left atrium and low ejection fraction were independent risk factors for new atrial fibrillation after pacemaker implantation.Conclusion: Through the clinical research on new atrial fibrillation after pacemaker operation,the following conclusions can be preliminarily drawn:1.The incidence of new atrial fibrillation within 1 year after pacemaker implantation is17.6% among patients who have no previous history of atrial fibrillation from 2010 to2018.Compared with common patients,the incidence of atrial fibrillation is higher.2.Patients with hypertension,diabetes,atrial premature or short atrial tachycardia,drinking history,overweight or obesity,UA,BNP,large left atrium and low ejection fraction are more prone to atrial fibrillation.Overweight or obesity,large left atrium and low ejection fraction are independent risk factors for new atrial fibrillation after pacemaker operation.3.The special function of pacemaker can effectively prevent atrial fibrillation,and r ATP function can effectively terminate atrial fibrillation after atrial fibrillation occurs. |