Analysis Of Risk Factors Of Esophageal-gastric Anastomotic Fistula After Esophageal Carcinoma

Objective:Risk factors of esophageal-gastric anastomotic fistula after radical resection of esophageal cancerMethods: Clinical data of 390 patients undergoing radical resection of esophageal carcinoma were analyzed retrospectively.Operation methods: the traditional thoracotomy group included left thoracotomy esophageal cancer radical surgery(Sweet)194 cases,transabdominal right thoracotomy two-cut esophageal cancer radical surgery(Ivor-Lewis)105 cases,transacervical right thoracotomy upper thoracotomy three-cut esophageal cancer radical treatment(McKeown)29 cases;minimally invasive group thoracoscopy combined with esophageal cancer radical surgery(TLE)62 cases.The counting data and grade variables were tested by χ2,and the P value less than 0.05 indicated that the difference between groups was statistically significant,and then the corresponding parameters were analyzed by binary Logistic regression analysis.Results: Single factor analysis showed that operation mode,accompanied with diabetes,hypertension,age,malignant tumor site,anastomotic site,operation time and postoperative serum albumin content were related to the occurrence of esophageal-gastric anastomotic fistula,and the difference between the two groups was statistically significant(P<0.05).Multivariate Logistic regression analysis showed that age is not an independent factordiabetes mellitus,hypertension,operation time and albumin content were independent risk factors for anastomotic fistula.Conclusion: Age,operation mode,anastomotic site are closely related to the occurrence of esophageal-gastric anastomotic fistula after esophageal cancer operation,and diabetes,hypertension,operation time and postoperative albumin content are the important causes of anastomotic fistula after esophageal cancer operation.