Developmental Characteristics Of Visual Evoked Potentials To Different Stimulation In Normal Children

Objective: To determine the developmental characteristics of flash visual evoked potentials(FVEP)and pattern-reversal visual evoked potentials(PVEP)of healthy children.Methods: The data were collected with a Keypoint Workstation multifunctional neuropotentiometer;166 children(2 months-13 years)were tested with FVEP and 101 children(4-13 years)were tested with PVEP.Results:(1)A triphasic waveform with clear components(N2,P2,and N3)was recorded steadily after 1 year,with occurrence rates over 97% at all frequencies.FVEP latency significantly decreased with age.The amplitude and amplitude difference of FVEP was greater for binocular than monocular fields.FVEP amplitude increased and amplitude differences decreased with stimulation frequency.(2)The occurrence rate of PVEP was100% after 4 years,and PVEP latency was significantly prolonged with age.N75 and P100 amplitudes and the N75-P100 amplitude difference increased with field of vision.Conclusion: FVEP can be evoked in normal children at less than 2Hz.Stimulation frequency can be adjusted to improve early detection and verification of subclinical lesions.The PVEP waveform is simple and stable,and its results are easier to analyze and interpret than FVEP,but it islimited by visual acuity and fixation force,whereas FVEP is affected less by visual acuity.but it is necessary to establish normal reference values of each age in each laboratory because of complicated analysis.According to the specific situation of the patient(visual acuity,fixation)and clinical demand,we need to choose the right stimulation.